Isotretinoin and other medications showed promising results for treating a rare scalp condition linked to severe acne.
December 2010 in “TSpace” Activating androgen receptors in muscle can increase muscle mass and reduce fat.
The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
Exercising women with irregular periods have lower thyroid hormone levels and less body fat.
Alopecia universalis may be linked to Down syndrome due to genes on chromosome 21.
December 2005 in “TSpace” Diode laser treatment effectively clears acne keloidalis nuchae.
July 2005 in “TSpace (University of Toronto)” Ghrelin and its receptors likely aren't risk factors for PCOS.
July 2004 in “TSpace (University of Toronto)” A rare case showed alopecia areata and lichen planus occurring together in one person.
408 citations
,
January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
232 citations
,
January 2016 in “BMC Bioinformatics” The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.
212 citations
,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
209 citations
,
October 2008 in “The Journal of Pathology” Stem cell niches are essential for tissue health and repair.
140 citations
,
December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
101 citations
,
November 2011 in “Nature Communications” Wnt/β-catenin signaling is crucial for cell fusion in placental development.
100 citations
,
March 2006 in “Journal of biological chemistry/The Journal of biological chemistry” Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
97 citations
,
January 2014 in “Journal of The American Academy of Dermatology” Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
96 citations
,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
89 citations
,
January 2021 in “Molecules” Biopolymeric composites need advanced properties for better use in medicine and healing.
88 citations
,
April 2012 in “Journal of Investigative Dermatology” Blocking TRPV3 may help treat itch in dry skin conditions.
88 citations
,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
78 citations
,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
76 citations
,
January 1998 in “Mammalian Genome”
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
52 citations
,
December 2020 in “Frontiers in Oncology” Chinese herbal medicine might help reduce chemotherapy side effects in breast cancer patients, but more high-quality research is needed.
50 citations
,
November 2021 in “Viruses” Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
45 citations
,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.