research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
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960-990 / 1000+ results research Determination of finasteride in human plasma by LC-MS and its pharmacokinetics
The method accurately measures finasteride in plasma, and the test tablets are as effective as the reference ones.
research 5α-Reductase: History and Clinical Importance
5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.
research Finasteride-its impact on sexual function and prostate cancer
Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.
research MP09-16 5-ALPHA REDUCTASE INHIBITORS FOR MALE LOWER URINARY TRACT SYMPTOMS: A COCHRANE SYSTEMATIC REVIEW AND META-ANALYSIS
5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.
research Iontophoretic Transdermal Delivery of Finasteride in Vesicular Invasomal Carriers
Finasteride delivery through skin improved using invasomes and iontophoresis.
research Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study.
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study
Dutasteride and finasteride cause kidney damage, with dutasteride being more harmful.
research Clinical assessment of CL22209, a standardized proprietary extract of Asparagus racemosus, for mitigating vasomotor and menstrual symptoms in perimenopausal women: A randomized, double-blind, placebo-controlled study
CL22209, an Asparagus racemosus extract, safely reduces perimenopausal symptoms and balances hormones.
research The effect of 5-α reductase inhibitor on Th1, Th2, and Th17 cell-related inflammatory response in BPH
Finasteride reduces some inflammation in BPH but not all.
research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach
The new gel formula could improve the delivery of a hair loss treatment through the skin and might be an alternative to taking it by mouth.
research Intraoperative Iris Behavior during Phacoemulsification Maneuvers in Rabbits Treated with Selective α1-Blocker, 5α-Reductase Inhibitor, or Anxiolytic Medication
Tamsulosin increases the risk of floppy iris during eye surgery.
research Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research Emerging medication for the treatment of male hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Rapid determination of finasteride in human plasma by UPLC–MS/MS and its application to clinical pharmacokinetic study
New method measures finasteride in blood quickly and accurately.
research Transdermal viprostol in the treatment of male pattern baldness
Viprostol does not effectively promote hair growth in male pattern baldness.
research Current treatment of BPH
TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
research Androgenic Effects on Ventricular Repolarization
ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
research Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database
Vismodegib can cause muscle spasms, taste changes, hair loss, fatigue, weight loss, and possibly new issues like skin cancer, dehydration, and swallowing problems, needing close monitoring.
research Finasteride/minoxidil
research Finasteride/minoxidil
research Finasteride/minoxidil
research DUTASTERIDE AS AN EFFECTIVE TREATMENT IN ANDROGENETIC ALOPECIA – A LITERATURE REVIEW
Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.
research Finasteride in Young Men: Effects on Semen and Hormones?
Finasteride improves hair but may reduce sperm quality at higher doses.
research Finasteride-related depression and suicidal ideation
research Global photographic assessment of men aged 18 to 60 years with male pattern hair loss receiving finasteride 1 mg or placebo
Finasteride significantly improves hair growth but may cause sexual side effects.
research Finasteride and Methadone Use and Risk of Advanced Hepatitis C Related Liver Disease
Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.
research Effectiveness and safety of finasteride in male chronic pelvic pain syndrome
Finasteride effectively reduces symptoms of male chronic pelvic pain syndrome with few side effects.
research Development of polymeric nanoparticles containing dutasteride for treatment of androgenic alopecia
Polymeric nanoparticles with dutasteride may effectively treat hair loss by targeting hair follicles.