58 citations
,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
57 citations
,
July 2018 in “Scientific Reports” Using adipose tissue-derived fragments improves early skin graft success.
45 citations
,
May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
44 citations
,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
44 citations
,
October 2011 in “Gynecological Endocrinology” Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
41 citations
,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
32 citations
,
June 2003 in “The American Journal of Dermatopathology” Lipedematous scalp is mainly caused by an increase in fat tissue under the skin and is different from lipedematous alopecia.
30 citations
,
February 2022 in “Stem Cell Reviews and Reports” Stem cell treatments may improve burn wound healing.
30 citations
,
July 2017 in “Stem cells and cloning” SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
25 citations
,
January 2001 in “Facial Plastic Surgery” Both tissue expansion and serial excision are effective for scar revision in the head and neck area.
24 citations
,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.
18 citations
,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
18 citations
,
March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
17 citations
,
January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
16 citations
,
April 2016 in “PLoS ONE” Negative pressure treatment improved skin thickness, blood vessel growth, and hair growth.
15 citations
,
January 2014 in “BioMed Research International” Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
14 citations
,
May 2019 in “Experimental Dermatology” Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.
13 citations
,
June 2020 in “Stem Cells International” A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
11 citations
,
June 2018 in “Sexual medicine reviews” Stromal Vascular Fraction might help with male sexual dysfunction, but more research is needed to confirm its safety and effectiveness.
10 citations
,
April 2019 in “Journal of Analytical Science and Technology” Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.
9 citations
,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
9 citations
,
May 2012 in “Journal of Craniofacial Surgery” Submental tissue is good for repairing mouth area skin with minimal scarring and good cosmetic results.
8 citations
,
April 2019 in “ACS Biomaterials Science & Engineering” The new SIS-PEG sponge is a promising material for skin regeneration and hair growth.
8 citations
,
November 2010 in “Facial Plastic Surgery” Fat transfer can be effective for soft tissue trauma if the patient is chosen carefully and the procedure is done correctly.
6 citations
,
January 2023 in “npj regenerative medicine” Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
6 citations
,
March 2018 in “Journal of Medicinal Food” Chicken egg yolk peptides can promote hair growth by increasing a specific growth factor.
5 citations
,
July 2019 in “Atlas of the Oral and Maxillofacial Surgery Clinics” Tissue expansion for head and neck reconstruction has good blood supply and doesn't need capsule removal, but expect temporary hair loss with normal growth resuming after 6-8 months.
4 citations
,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
4 citations
,
January 2018 in “International Journal of Immunopathology and Pharmacology” Fat tissue transplant may be an effective new treatment for severe, treatment-resistant hair loss from folliculitis decalvans.
4 citations
,
November 2015 in “Aesthetic Plastic Surgery” Using tissue expanders for scalp reconstruction in patients with extensive Aplasia Cutis Congenita is effective and has minimal complications.