1 citations
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June 2021 in “General physiology and biophysics” Minoxidil relaxes rat blood vessels mainly through nitric oxide and potassium channels.
90 citations
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January 1989 in “PubMed” 40 citations
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July 2011 in “The journal of clinical hypertension” Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.
January 2024 in “Life sciences” Testosterone affects blood vessel relaxation in hypertensive rats.
34 citations
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July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
34 citations
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June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
1 citations
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January 2014 in “Research Journal of Pharmacognosy and Phytochemistry” Hibiscus root extract reduces inflammation in rats.
28 citations
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August 2013 in “Hypertension” Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
25 citations
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December 1974 in “Clinical Pharmacology & Therapeutics” Propranolol affects heart rate and renin levels in minoxidil-treated patients.
3 citations
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December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal” Compound 3 protects the heart from damage by activating A1-adenosine receptors.
1 citations
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March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
April 2017 in “The Journal of urology/The journal of urology” SHH protein helps nerve regeneration in hypertensive rats.
57 citations
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February 1975 in “Journal of Clinical Investigation” Minoxidil boosts plasma renin activity, influenced by control plasma renin activity and changes in sympathetic tone.
February 2025 in “Brazilian Journal of Hair Health” Multiparametric ultrasound effectively monitors scalp changes after using vasoconstrictive cosmetics.
18 citations
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October 2020 in “Journal of Pharmacology and Experimental Therapeutics” KATP channel openers may cause peripheral edema by reducing lymphatic contractions and flow.
35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
1 citations
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October 1974 in “Postgraduate medicine” New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
1 citations
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June 2023 in “Frontiers in Pharmacology” Vasodilators may worsen abdominal aortic aneurysm.
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November 1994 in “Archives of Biochemistry and Biophysics” 28 citations
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May 2023 in “Current Opinion in Colloid & Interface Science”
17 citations
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February 2009 in “Journal of Ethnopharmacology” Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
April 2019 in “International research journal of pharmacy” Adiantum capillus extract reduces pain and swelling in animals.
26 citations
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June 1983 in “Journal of Hypertension” Minoxidil lowers blood pressure more effectively but has more side effects, so try hydralazine first.
66 citations
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September 1982 in “Biochemical Pharmacology” Liver enzyme helps minoxidil work better for blood vessel relaxation.
March 2025 in “Journal of Cosmetic Dermatology” Botulinum toxin type A may widen certain arteries, but more research is needed.
2 citations
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July 2019 in “International Journal of Neuroscience and Behavioral Science” Thevetia peruviana bark extract reduces pain in mice and may help create new painkillers.
1 citations
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June 2015 in “Journal of anatomy” A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
2 citations
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February 2020 in “Rivista Urologia” Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
1 citations
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August 1989 in “Archives of Dermatology” Minoxidil may promote hair growth by mimicking a natural body process.