January 2020 in “Journal of dermatology research and therapy” Most over-the-counter hair loss treatments lack strong evidence of effectiveness but cost nearly as much as the proven treatment, minoxidil.
55 citations
,
November 2019 in “Cellular and Molecular Gastroenterology and Hepatology” Biotin may help treat inflammatory bowel disease by reducing inflammation and improving gut health.
2 citations
,
July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
1 citations
,
August 2004 in “Alternative & complementary therapies” Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.
September 2024 in “African Journal of Biomedical Research” Alopecia areata patients have lower vitamin D and slightly lower copper levels, so these should be checked.
20 citations
,
May 2016 in “Journal of Cosmetic Dermatology” Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.
13 citations
,
August 2020 in “Journal of Laparoendoscopic & Advanced Surgical Techniques” Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
3 citations
,
January 2017 in “Journal of cosmetology & trichology” The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.
2 citations
,
January 1997 in “Journal of Clinical Biochemistry and Nutrition” Biotin deficiency causes severe hair loss and weight reduction in germ-free mice.
40 citations
,
January 2022 in “Nutrients” Diet can influence inflammatory skin diseases.
July 2024 in “Skin Appendage Disorders” The supplement significantly improves hair density and appearance in people with hair loss.
27 citations
,
September 2017 in “Journal of Medicinal Food” Annurca apple supplement safely increases hair growth and keratin in humans.
11 citations
,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
78 citations
,
January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
10 citations
,
September 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
August 2023 in “Natural Resources for Human Health” Vegetarians should take B vitamin supplements to avoid health issues.
5 citations
,
December 1942 in “Journal of the American Medical Association” Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.
82 citations
,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
December 2025 in “Frontiers in Nutrition” Collagen supplements may improve skin, joints, and recovery, especially with added nutrients.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
9 citations
,
March 2014 in “TURKDERM” Proper nutrition is crucial for healthy hair growth.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
13 citations
,
January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
May 2025 in “Health Science Reports” Serum WS Biotin significantly reduces hair shedding and improves hair thickness.
2 citations
,
January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
41 citations
,
March 2007 in “Journal of dermatological science” Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
October 2023 in “International Journal of Cosmetic Science” WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
May 2026 in “International Journal of Creative and Open Research in Engineering and Management” A balanced diet and healthy lifestyle are crucial for preventing hair loss.
1 citations
,
April 2021 in “International Journal of Research in Dermatology” Low iron and vitamin B12 levels are common in women with chronic hair loss, while low vitamin D is less common.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” The best biotin hair tonic formula has 20% span 80, 9.47% tween 80, and 5% PEG 400.