research METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α
Targeting METTL1 may help slow papillary thyroid cancer growth and spread.
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research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
research Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Generation of Induced Pluripotent Stem Cells from Hair Follicle Bulge Neural Crest Stem Cells
Hair follicle stem cells need all reprogramming factors to become pluripotent.
research Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers
Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
research Inducible, reversible hair loss in transgenic mice.
Scientists made a mouse that can be made to lose hair and then grow it back.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Plant-Produced Basic Fibroblast Growth Factor (bFGF) Promotes Cell Proliferation and Collagen Production
Plant-made bFGF helps cells grow and boosts collagen.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing β-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets
Angelica gigas Nakai root extracts may help with cancer, pain, memory loss, and metabolic issues.
research Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice
Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
research Transgenic HPV11-E2 protein modulates URR activity in vivo
The E2 protein affects gene activity in hair follicles of mice.
research The PER3 rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria
The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli
KGF-1 135 is a stable and effective alternative for treating oral mucositis.
research The SYP123-VAMP727 SNARE complex is involved in the delivery of inner cell wall components to the root hair shank in Arabidopsis
The SYP123-VAMP727 complex is important for transporting materials that harden the root hair shank in Arabidopsis.
research A comparative study of materials assembled from recombinant K31 and K81 and extracted human hair keratins
Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
research Increase in IL-15 levels in patients with alopecia areata
Higher IL-15 levels are linked to more severe hair loss in alopecia areata.
research Induction of hyperandrogenism and insulin resistance differentially modulates ferroptosis in uterine and placental tissues of pregnant rats
HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research Role of the Wnt signaling pathway in keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research Ethanol extract of medicinal herbal mixture accelerates hair growth and melanogenesis in vivo and in vitro
A herbal extract can boost hair growth and pigmentation like minoxidil.
research Knockout of p16INK4a promotes aggregative growth of dermal papilla cells
Removing p16INK4a from skin cells can lead to faster and more clumped growth, which might help with hair growth.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Proceedings of the RAMI Intern Section Meeting, 18th January 2014
The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
research Low level of maternal biotin intake changes the expression of biotin transporter in dams and fetuses in mice
Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.
research ROS-scavenging microneedles loaded with Portulaca oleracea L.-derived exosomes for atopic dermatitis therapy
A new microneedle patch effectively treats atopic dermatitis by reducing skin stress and restoring immune balance.
research CD4 expression controls epidermal stem cell balance
CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
research Effects of platelet-rich fibrin on repair and healing chronic refractory wounds in rats by regulating Wnt/b-catenin signalling pathway
Platelet-rich fibrin helps heal stubborn wounds in rats by reducing inflammation and boosting tissue repair.
research Mucosal TLR5 activation controls healthspan and longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.