May 2026 in “The EMBO Journal” The document explores the mechanisms of skin aging, emphasizing the roles of cellular senescence, disrupted communication between skin layers, and dysregulation of the microbiome and hormonal signaling in compromising skin structure and function. It discusses advances in evaluating skin aging through molecular and phenotypic indices, which help assess biological age and the effectiveness of interventions. The paper also highlights rejuvenation strategies, including gene expression rewiring, metabolic and microenvironmental modulation, microbiome adjustments, and hormone regulation, providing a framework for precision interventions and regenerative therapies.
2 citations
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February 2021 in “Developmental Cell” Middle-aged skin shows aging signs, and quercetin might help delay them.
October 2021 in “Journal of Investigative Dermatology” The study concludes that as skin matures from infancy to childhood, there are major changes in cell differentiation, stemness, and growth, leading to a stronger skin barrier in older children.
22 citations
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July 2024 in “Archives of Plastic Surgery” Injectable skin boosters effectively rejuvenate aging skin by improving hydration and elasticity.
2 citations
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January 2000 in “Pediatrics in review” Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.
1 citations
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May 2017 in “Journal of The American Academy of Dermatology” The moisturizer with phytol improved skin texture and reduced fine wrinkles better than the moisturizer without it.
November 2019 in “Monatsschrift Kinderheilkunde” The document concludes that pediatricians play a vital role in supporting adolescents through puberty and should enhance their competence in this area.
26 citations
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March 2018 in “Dermatology and Therapy” EPC-CM can reduce skin aging signs by boosting the skin's defense system.
14 citations
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May 2023 in “Dermatologic Surgery” VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.
1 citations
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September 2025 in “Journal of Cosmetic Dermatology” The framework suggests sun protection, retinoids, and antioxidants to improve skin longevity.
22 citations
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September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
2 citations
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July 2025 in “Journal of Cosmetic Dermatology” Cosmetic dermatology is improving with new technologies but faces ethical and regulatory challenges.
July 2023 in “AYUSHDHARA” Aging is a natural process causing physical and mental decline.
17 citations
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May 2023 in “Aesthetic Plastic Surgery” Stem cell therapies show the most promise for anti-aging benefits.
15 citations
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December 2013 in “Clinical Cosmetic and Investigational Dermatology” MAGP-1 decreases with age, leading to weaker, sagging skin.
7 citations
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August 2023 in “Skin Research and Technology” Scalp conditions change with age, affecting hair health.
11 citations
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December 2016 in “Frontiers in Psychology” Hair style affects perceptions of age, health, and attractiveness more than hair color does.
January 2018 in “Journal of general practice” Young people are losing hair due to stress, poor diet, pollution, and lack of sleep, but it can be treated with supplements and scalp treatments.
November 2022 in “Journal of Investigative Dermatology” Botanical extract improved well-being and skin health in a test group compared to a placebo.
55 citations
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August 2015 in “AAPS PharmSciTech” The cream with orange peel and liquorice extracts may help reduce skin aging.
51 citations
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November 2018 in “JAMA Dermatology” PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.
6 citations
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July 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
July 2023 in “Ageing & Longevity” The document concludes that aging can be tackled by either slowing it down or eliminating its root cause.
November 2022 in “Journal of Investigative Dermatology” The LED light therapy mask improved skin elasticity and reduced signs of aging in a test and in women aged 40-60.
July 2020 in “RePub (Erasmus University, Rotterdam)” Facial skin aging is influenced by wrinkles, spots, genetics, and environment.
3 citations
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May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
October 2023 in “Dermatological reviews” Fibroblast-derived growth factors and exosomes can significantly improve skin aging.
3 citations
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February 2025 in “Life” PRP and fibrin treatments improve skin thickness and density, regardless of age.
14 citations
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September 2024 in “Cosmetics” Exosomes and cell culture-conditioned media improve skin quality and reduce aging signs.
1 citations
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November 2023 in “Dermatological Reviews” Future skincare will use advanced science for personalized anti-aging treatments.