research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
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510-540 / 1000+ results research Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Expansion Culture of Hair Follicle Stem Cells through Uniform Aggregation in Microwell Array Devices
The new microwell device helps grow more hair stem cells that can regenerate hair.
research Rescuing key native traits in cultured dermal papilla cells for human hair regeneration
Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Fabrication of Bilayer Nanofibrous-Hydrogel Scaffold from Bacterial Cellulose, PVA, and Gelatin as Advanced Dressing for Wound Healing and Soft Tissue Engineering
The scaffold is a promising material for wound healing and tissue engineering.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles
Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.
research Organoids in skin wound healing
Skin organoids help improve wound healing and tissue repair.
research Micropatterned dermal–epidermal regeneration matrices create functional niches that enhance epidermal morphogenesis
The new matrix improves skin regeneration and graft performance.
research Skin‐on‐a‐chip strategies for human hair follicle regeneration
New technologies show promise for better hair regeneration and treatments.
research Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury
A silk fibroin hydrogel boosts wound healing and hair growth by increasing collagen and hair follicles.
research The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation
The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
research Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration
Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism
Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
ASC-CM is more effective than EV for treating osteoarthritis.
research Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia
Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
research A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies
Personalized skin rejuvenation using genomics shows promise but needs more research.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research Switching roles: the functional plasticity of adult tissue stem cells
Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.
research Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation
New skin repair methods show promise but need to be safer and more accessible.
research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Human hair follicles can provide stem cells for regenerative medicine.
research Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control
Functionalized hydrogels can help heal tissues and fight infections by delivering beneficial bacteria and antimicrobials.