research The First Syntheses of 16β-Chloro- and 16β-Bromo-cyproterone Acetate
Scientists made two new chemicals that might help treat diseases caused by male hormones.
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research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination
The ASIP gene is crucial for determining cattle coat color.
research Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53
Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.
research Simultaneous quantitative analysis of tamsulosin and finasteride in pharmaceutical dosage form by U-HPLC Tandem mass spectrometry
Method measures tamsulosin and finasteride in medicine accurately.
research Comparison of Finasteride and Dutasteride on Risk of Prostate Cancer in Patients with Benign Prostatic Hyperplasia: A Pooled Analysis of 15 Real-world Databases
Dutasteride and finasteride have similar effects on prostate cancer risk in BPH patients.
research Assessment of Optimism in Women with Polycystic Ovary Syndrome: A Case Control-Study
Women with PCOS tend to be less optimistic than those without it.
research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland
Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
![Integrating Multi-Omics Analyses of Nonomuraea Dietziae to Reveal the Role of Soybean Oil in [(4′-OH)MeLeu]4-CsA Overproduction](/images/research/0eba9759-3aa4-4a06-a70a-2d9c46be53f3/small/23018.jpg)
research Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu]4-CsA overproduction
Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.
research Caracterização e diferenciação neural in vitro de células-tronco de polpa de dente decíduo humano
Dental pulp stem cells might not reliably become neurons.
research Assessment of the Ability of the ChatGPT-5 Model to Pass the Endocrinology Specialization Exam
ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.
research Hereditary vitamin D resistant rickets (HVDRR) case series: phenotype, genotype, conventional treatment, and adjunctive cinacalcet therapy
Cinacalcet may help treat hereditary vitamin D resistant rickets safely.
research Safety and Efficacy of Oral administrated Cepharanthine in Non-hospitalized, asymptomatic or mild COVID-19 patients: A Double-blind, Randomized, Placebo-controlled Trial
Cepharanthine is safe but not clearly effective in speeding up COVID-19 recovery.
research Free Androgen Index (FAI): Marker of Premature Androgenetic Alopecia in Men
The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
research Clinical Predictors of Outcome in Nonsegmental Vitiligo: A Prospective Cohort Study
Certain skin and family history markers predict vitiligo severity and treatment needs.
research 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish
The development of breeding tubercles in male zebrafish relies on a specific enzyme that processes hormones.
research Analysis of Keratin-Associated Protein-7 (KRTAP7) protein structure and function in Indian dromedary camel (Camelus dromedarius)
All Indian dromedary camel breeds have the same KRTAP7 gene affecting hair quality.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats
Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.
research Association between geriatric nutritional risk index and fecal incontinence in individuals with stroke: mediating roles of systemic immune inflammation index and oxidative balance scores
Better nutrition may reduce fecal incontinence in stroke patients by lowering inflammation and improving antioxidant levels.
research Association between SQSTM1 dysregulation and risk in alopecia areata: a Mendelian randomization study
SQSTM1 gene issues may increase the risk of alopecia areata.
research Formulation Development and Evaluation of Herbal Hair Oil
Herbal hair oil formulations A4 and A5 effectively promote hair growth and stability.
research Immunomodulatory Effects of Platelet-Rich Plasma (PRP) on Neuroinflammation: Insights from B92 Glial Cells Stimulated with Heat-Killed Escherichia coli
PRP may help reduce brain inflammation and protect brain cells.
research Phenolic profile of leaves obtained from autochthonous grapevine cultivars in Isparta Province of Türkiye
White grapevine leaves, especially 'Razaki', have high phenolic content, useful for health products.
research DESENVOLVIMENTO BIOTECNOLÓGICO DE SÉRUM REJUVENESCEDOR ANTIOXIDANTE CONTENDO ATIVO LIPÍDICO ORIUNDO DA RANA CATESBEIANA SHAW
The serum is effective, safe, and stable for skincare.
research The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat-High-Fructose-Induced Insulin Resistance Swiss-Webster Male Mice
Allium ascalonicum L. extract may help improve insulin resistance.
research Comparative analysis of stemness between dermal papilla cells and human dermalstem/progenitor cells
Human dermal stem/progenitor cells can divide and differentiate more than hair follicle dermal papilla cells.
research Birth Outcomes of Infants Born to Mothers with Alopecia Areata: A Nationwide Population-based Study in Korea
Mothers with alopecia areata have a higher risk of adverse birth outcomes.
research Polarized microscopy in genetic hair disorders: case series
Polarized microscopy helps identify hair irregularities in genetic disorders.
research Unlocking the genetic secrets of Dorper sheep: insights into wool shedding and hair follicle development
Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.