132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
77 citations
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July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
76 citations
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May 2007 in “Menopause International” After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.
41 citations
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May 2018 in “Nutrition and healthy aging” Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
36 citations
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September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
23 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
16 citations
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June 2019 in “Journal of Investigative Dermatology” miR-21 increases skin aging by reducing SATB1, affecting skin cell function.
13 citations
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March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
9 citations
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January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
8 citations
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July 2024 in “Cells” PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
7 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
6 citations
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September 2019 in “Journal of cosmetic dermatology” Lower melatonin levels are linked to more skin aging.
6 citations
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September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.
3 citations
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October 2023 in “Frontiers in physiology” ceRNA networks offer potential treatments for skin aging and wound healing.
2 citations
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April 2011 in “InTech eBooks” Non-denatured soybean extracts provide multiple anti-aging skin benefits.
2 citations
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October 1962 in “Archives of Dermatology” Surgical methods can't treat gray hair, hair loss, or thinning skin.
1 citations
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October 2025 in “Beni-Suef University Journal of Basic and Applied Sciences” Lipid-based nanocosmeceuticals improve skin therapy by enhancing ingredient delivery and effectiveness for anti-aging and skin disorders.
1 citations
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April 2025 in “JOJ Dermatology & Cosmetics” The collagen booster may improve healing after CO2 laser treatment for skin aging.
1 citations
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February 2025 in “Journal of Biomedical Research & Environmental Sciences” Mushroom extracts can help with anti-aging, skin care, and hair loss in cosmetics.
1 citations
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August 2024 in “PubMed” Carboxytherapy can improve and reverse aging skin.
Regenerative cosmetics can improve skin and hair by reducing wrinkles, healing wounds, and promoting hair growth.
1 citations
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June 2022 in “Experimental dermatology” The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” The plant combination effectively repairs skin and delays aging.
September 2022 in “PubMed” Collagen type XVII α1 decreases with age, leading to skin aging, but targeting microRNA-203b-3p may help maintain its levels and improve skin health.
May 2021 in “Клітинна та органна трансплантологія” Skin aging can be slowed down with proper care and treatments.
January 2015 in “Springer eBooks” Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
180 citations
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January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
68 citations
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September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
9 citations
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March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.