82 citations
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January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
55 citations
,
June 2012 in “Steroids” Testosterone affects vascular cells directly without converting to estradiol.
46 citations
,
April 1982 in “Journal of the American Academy of Dermatology” Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.
43 citations
,
August 2016 in “Scientific Reports” Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
39 citations
,
May 2002 in “Oral Microbiology and Immunology” Testosterone increases cell growth and reduces IL-6 in gum cells.
37 citations
,
November 1995 in “Journal of Investigative Dermatology” Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
26 citations
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March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
24 citations
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January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
24 citations
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February 2007 in “Hormone and metabolic research” The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
14 citations
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April 1978 in “International Journal of Dermatology” Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
13 citations
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August 2016 in “Reproduction” High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
13 citations
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November 2010 in “Experimental Dermatology” Vitamin C derivative reduces hair loss-related protein in cells.
10 citations
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May 2019 in “International Journal of Environmental Research and Public Health” Finasteride may cause kidney damage.
8 citations
,
May 2011 in “Journal of Pharmacology and Experimental Therapeutics” Dosing time affects finasteride's effectiveness and safety in rats.
7 citations
,
April 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
7 citations
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August 2006 in “Maturitas” Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
3 citations
,
March 2018 in “European Urology Supplements” Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.
2 citations
,
January 2025 in “Frontiers in Pharmacology” Purple corn extract may help reduce prostate enlargement and inflammation.
2 citations
,
September 2024 in “Animal Cells and Systems” Hepatitis B virus alters steroid hormones in male mice, reducing dihydrotestosterone to inhibit viral replication.
1 citations
,
April 2024 in “Food Frontiers” Pu-erh tea reduces hair loss risk in offspring.
1 citations
,
March 2021 in “Phytomedicine plus” Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
1 citations
,
January 2021 in “Open Access Journal of Cancer & Oncology” Energy healing treatment improved flutamide's solubility and stability, potentially enhancing its effectiveness for prostate cancer.
1 citations
,
April 2014 in “Journal of the Korean Society of Food Science and Nutrition” Unripe Rubus occidentalis extracts may help treat benign prostatic hyperplasia.
November 2025 in “PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS” Taurine may help reduce hair loss by improving hair growth cycles.
September 2025 in “Medicine & Science in Sports & Exercise” Gender-affirming hormone therapy and surgery affect gut bacteria differently.
November 2024 in “Journal of Cosmetic Dermatology” The plant extracts may help treat hair loss by promoting hair growth and reducing DHT levels.
September 2023 in “Gynäkologische Endokrinologie” Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.
August 2019 in “KMOU Repository (Korea Maritime and Ocean University)” Sapium rotundifolium extract may help treat enlarged prostate.
Finasteride affects prostate development differently in male and female Mongolian gerbils.
March 2014 in “The Journal of Urology” Finasteride increases CD8+ T cells in BPH tissues.