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Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Higher cholesterol levels increase aggressive prostate cancer risk.

Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.

Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

A new microneedle treatment shows promise for better hair regrowth in androgenetic alopecia.

DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

Tadalafil and Finasteride may help treat aggressive melanoma.

Synthetic curcumin derivatives improve treatment for diabetes and cancer.

SARS-CoV-2 may worsen IPF due to shared genes and pathways, suggesting potential drug targets.

Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.

SGK1 is important in cancer growth and treatment resistance, and targeting it could improve therapies.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Male pattern baldness is linked to specific genetic variations in the androgen receptor gene.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

ERG increases SOX9, promoting prostate cancer growth and invasion.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Blocking testosterone speeds up wound healing in males.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.