research Three-Dimensional Printing in Trichology: A Narrative Mini-Review – Where Are We Now?
3D bioprinting could help treat hair loss, but it needs more work and cost reduction for real-world use.
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30 / 1000+ resultsresearch Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research 890 Development of pigmented reconstructed human epidermis model containing human melanoblasts from keratinocyte culture
The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
research Tissue Engineering in Cosmetics and Dermatology: A New Era of Innovation and Application
Tissue engineering in cosmetics offers safer, more effective products and ethical alternatives to animal testing.
research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Bioprinting is improving skin models for better testing of skin diseases without using animals.
research Development of an in Vitro Inhalation Method for Characterization of Aerosols Released During the Use of Hair Products
A new lab method helps assess respiratory risks of hair product aerosols without animal testing.
research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research
Hair organoids are effective for testing hair loss treatments.
research Optimization of Gelatin and Crosslinker Concentrations in a Gelatin/Alginate-Based Bioink with Potential Applications in a Simplified Skin Model
A bioink with 15% gelatin and 150 mM calcium chloride works best for 3D printing skin models.
research Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro
A 3D skin model helps study wound healing better than traditional methods.
research Cutaneous Permeation and Penetration of Sunscreens: Formulation Strategies and In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths
PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
research Fish Cell Spheroids, a Promising In Vitro Model to Mimic In Vivo Research: A Review
Fish cell spheroids are a promising tool for replicating real-life conditions in research.
research Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution
Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
research Improved forensic hair evidence for drugs of abuse by mass spectrometry
Forensic hair analysis for drugs is now more reliable and accurate.
research Refractory Dermatophytosis in a Spitz Dog Successfully Managed with Posaconazole: A Case Report
Posaconazole successfully treated a resistant skin infection in a Spitz dog when other antifungals failed.
research Changes in European Legislation Make it Timely to Introduce a Transparent Market Surveillance System for Cosmetics
Europe needs a clear system to watch over cosmetics for safety and to make sure product claims are true.
research Impact of Cernitin™ on induced chronic prostatitis in animal model for understanding management of lower urinary tract symptoms
Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
research Production of ultraviolet-light-induced skin erythema in the hairless rat: a comparison with the haired rat in screening for anti-inflammatory drugs
Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion
The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
research DERMATOLOGICAL AND SYSTEMIC REACTIONS TO HAIR DYES: CURRENT EVIDENCE AND MANAGEMENT
Hair dyes, especially with PPD, can cause skin and rare systemic reactions, and safer alternatives are needed.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Development of a DNA-analytical Method for the Identification of Animal Hair Fibers in Textiles
Researchers developed a new method to identify animal hair in textiles, which is effective for various fibers and more reliable than previous methods.
research Anti-keratin Monoclonal Antibodies for Identifying Animal Hair Fibers
Scientists made antibodies to tell cashmere and wool apart, which could improve how we identify animal fibers.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.