6 citations
,
February 2023 in “Cosmetics” Nostoc verrucosum extracts may help reduce melanin production and have antioxidant properties.
33 citations
,
January 2015 in “Journal of Ginseng Research” Ginsenoside Rg3 from Panax ginseng can lighten skin by reducing melanin production.
18 citations
,
September 2016 in “International Journal of Molecular Sciences” Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
Heated radish extract may help lighten skin and reduce aging signs.
4 citations
,
December 2024 in “International Journal of Molecular Sciences” Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” CMC2.24 and CMC2.23 reduce melanin safely and effectively.
18 citations
,
February 2023 in “Plants” Purple glutinous rice extracts can help whiten skin and reduce aging signs.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
February 2025 in “Intisari Sains Medis” PDRN from salmon may slow skin aging by improving skin quality and reducing inflammation.
15 citations
,
August 2014 in “Journal of dermatological science” Pueraria thunbergiana extract may help prevent hair from turning gray.
4 citations
,
July 2021 in “Skin Appendage Disorders” Sudden hair whitening may be linked to immune system activity.
April 2025 in “Pharmacognosy Magazine” Compound Baqia Danshen Liniment may effectively treat vitiligo by improving skin and hair pigmentation and reducing inflammation.
April 2025 in “Journal of Skin and Stem Cell” PDRN from trout sperm helps skin and hair regeneration but is costly and complex to produce.
9 citations
,
November 2022 in “Applied sciences” Marine algae compounds may improve skin health and promote hair growth.
Marine macroalgae contain compounds that can improve skin health and have cosmetic benefits.
August 2024 in “Drug Design Development and Therapy” Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
17 citations
,
February 2015 in “Phytochemistry Reviews” Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.
August 2025 in “World Academy of Sciences Journal” Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
28 citations
,
December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
40 citations
,
January 2013 in “Clinical Cosmetic and Investigational Dermatology” Desonide is more effective than niacinamide for reducing underarm darkening.
34 citations
,
October 2024 in “Clinical Cosmetic and Investigational Dermatology” Azelaic acid is effective for treating rosacea, acne, and melasma.
3 citations
,
January 2022 in “Journal of drugs in dermatology” Rice bran extract can help with hair growth, thickness, and color.
Bee venom can improve various skin conditions, including varicose veins and psoriasis, and has anti-aging benefits.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
January 2013 in “Anti-infection Pharmacy” Ligustri Lucidi Fructus has potential benefits for skin health, including anti-inflammation, anti-allergy, and promoting hair growth.
25 citations
,
August 2015 in “Molecules” Mimosine dipeptides are promising for treating hyperpigmentation and inflammation.
December 2025 in “MEDFARM Jurnal Farmasi dan Kesehatan” Topical metformin shows promise for treating skin conditions like acne and psoriasis.
7 citations
,
March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
9 citations
,
July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
November 2022 in “Journal of Investigative Dermatology” Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.