research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
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570-600 / 1000+ resultsresearch Advances in Longevity: The Intersection of Regenerative Medicine and Cosmetic Dermatology
Cosmetic dermatology is improving with new technologies but faces ethical and regulatory challenges.
research A variety of processes that affect the perception of skin aging
Changing habits can make you look younger and improve your overall health.
research The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review.
Topical CoQ10 can reduce wrinkles and signs of aging.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.
research 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research Appearance and Internal Aging
Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.
research 567 Skin aging and carcinogenesis mechanisms by focusing on the stem cell competitive dynamics
Skin aging and cancer development are influenced by the competition between stem cells.
research Targeting the hallmarks of aging: preclinical evidence and molecular mechanisms underlying the therapeutic potential of Centella asiatica (L.) Urban
Centella asiatica may help extend healthspan by targeting aging processes.
research Skin aging: are adipocytes the next target?
Targeting dermal adipocytes may help combat skin aging.
research Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
research Living longer, looking lovely
Caloric restriction may extend life but doesn't improve appearance, and modern eating habits need reevaluation.
research Facial Skin Aging: a multidimensional phenotype
Facial skin aging is influenced by wrinkles, spots, genetics, and environment.
research Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research Hand rejuvenation
The hand rejuvenation method makes hands look younger by improving skin and filling out tissues.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research The Future of Topical Therapy for Cutaneous Aging
New treatments for skin aging will soon compete with current ones like tretinoin.
research Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
research Local IL-17 orchestrates skin aging
Blocking IL-17 signaling can delay skin aging and improve skin and hair health.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research 1408 Men’s skin needs energy for proper skin recovery & the combination of compounds A & B exhibits strong antioxidant and energy-amplifying benefits
Compounds A and B help men's skin recover faster by reducing oxidative damage and increasing energy levels.
research The Role of PGC-1α in Aging Skin Barrier Function
PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
research STRESS AND AGING*
Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.
research Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging
Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
research Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging
Stem cell-derived therapies can help rejuvenate skin by improving wrinkles, elasticity, and pigmentation.
research 1313 Fzd2 controls multiple aspects of epidermal development through distinct signaling mechanisms
Fzd2 is important for skin and hair development through various signaling ways.
research 1314 Advanced age impairs self-renewal and biases fate choice of hair follicle dermal stem cells
Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
research 1315 An Integrated model of alopecia areata biomarkers highlights both Th1/Th2 upregulation, with stronger correlations between Th2 activation and disease severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.