June 2023 in “Frontiers in Medicine” Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
12 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
415 citations
,
January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
84 citations
,
February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
46 citations
,
September 2023 in “Cell Reports” Sebaceous glands can regenerate after injury using stem cells from hair follicles.
18 citations
,
July 2024 in “Frontiers in Immunology” Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
13 citations
,
July 2020 in “World journal of stem cells” Vitamin D and calcium are important for skin stem cell function and wound healing.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” Xenopus laevis tadpoles can regenerate complex tail structures, offering insights for regenerative medicine.
2 citations
,
June 2025 in “Biomolecules” Microbiome analysis, BEVs, and AI can improve PCOS diagnosis and treatment.
January 2026 in “Nature Reviews Urology” January 2026 in “Pharmaceutics” Nanotechnology in skincare improves ingredient stability, skin penetration, and controlled release for better cosmetic solutions.
29 citations
,
April 2000 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” ICAM-1 helps regulate hair growth cycles and skin remodeling.
57 citations
,
January 2022 in “Biomedicines” Curcumin may improve cancer radiotherapy by making cancer cells more sensitive to radiation and protecting normal cells.
30 citations
,
June 1993 in “The Journal of Cell Biology” The oncoprotein causes abnormal hair growth without increasing skin cancer risk.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
158 citations
,
June 2017 in “Maturitas” Estrogen helps improve skin aging and healing, especially in post-menopausal women.
68 citations
,
April 2014 in “Journal of Investigative Dermatology” Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
48 citations
,
April 2021 in “Pharmaceuticals” Liposomal curcumin improves skin cancer treatment effectiveness while sparing normal cells.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
37 citations
,
August 2024 in “Current Issues in Molecular Biology” Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
37 citations
,
February 2010 in “Psychoneuroendocrinology” Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
36 citations
,
May 2025 in “Antioxidants” Lipid peroxidation worsens skin diseases but may help treat cancer.
35 citations
,
April 2024 in “Life” Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
19 citations
,
November 2022 in “Antioxidants” Ginger peel polysaccharides modified with zinc effectively reduce inflammation.
18 citations
,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
17 citations
,
January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
15 citations
,
June 2024 in “Frontiers in Pharmacology” Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
13 citations
,
March 2024 in “Cell Transplantation” Engineered skin tissue is a promising tool for safer cosmetic testing.