September 2025 in “Journal of Science Innovations and Nature of Earth” Anthocyanins in berries and purple veggies offer health benefits but need better processing for full use.
26 citations
,
July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
36 citations
,
October 2019 in “Cell Proliferation” Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” CMC2.24 and CMC2.23 reduce melanin safely and effectively.
March 2026 in “Preprints.org” Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
December 2017 in “JURNAL FARMANESIA” Red dragon fruit peel extract can effectively dye gray hair black.
1 citations
,
April 2025 in “Phycology” Phlorotannins from brown seaweeds may improve skin and hair health in cosmetics.
5 citations
,
November 2017 in “Asian Journal of Beauty and Cosmetology” Sinapic acid may protect skin cells from UV damage and reduce inflammation, making it a promising anti-aging cosmetic ingredient.
7 citations
,
September 2021 in “Journal of Applied Polymer Science” Cuttlefish ink melanin protects hair from UV damage.
13 citations
,
September 2022 in “Materials & design” The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.
4 citations
,
December 2024 in “International Journal of Molecular Sciences” Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.
10 citations
,
March 2010 in “Journal of Food Biochemistry” Tamarind seed coats have strong antioxidant properties and could be used in health products and food preservatives.
18 citations
,
July 2001 in “Australian veterinary journal” A cat with skin bumps and itching had high blood fats and skin infections, which improved with diet and medication changes.
6 citations
,
November 2021 in “Journal of Ethnopharmacology” Calanthe orchids have medicinal potential and contain 265 chemical compounds, but are underexplored.
January 2023 in “Journal for ReAttach Therapy and Developmental Diversities” Carthamus oxyacantha may help treat BPH by inhibiting 5α-reductase.
August 2024 in “Bionatura journal :” The hydromethanolic extract of Carthamus caeruleus L. rhizome is a strong antioxidant and can kill cancer cells.
62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
17 citations
,
April 2004 in “Acta Clinica Belgica” UV light makes skin signs of lack of carotene and vitamin A more visible.
61 citations
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September 2010 in “Fitoterapia” Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.
Mangosteen peel extract may promote hair growth and darken hair color.
1 citations
,
December 2024 in “Case Reports in Dermatology” Cyclophosphamide likely causes skin darkening by affecting hair follicles.
March 2026 in “Pharmaceuticals” Xiaoban Kangfu capsules contain compounds that may help with antioxidants, reducing inflammation, and promoting hair growth.
1 citations
,
January 2025 in “Regenerative Biomaterials” Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
3 citations
,
May 2020 in “Acta pharmaceutica” Protocatechuic acid can reduce melanin production and boost antioxidant activity in hair follicles.
7 citations
,
January 2018 in “Indian Journal of Pharmacology” Algerian Carthamus caeruleus L plant has anti-inflammatory properties, heals wounds effectively, and may help with hair growth.
10 citations
,
January 2016 in “ACG Case Reports Journal” Long-term Cape Aloe use causes harmless colon pigmentation that can help detect polyps.
4 citations
,
October 2021 in “International Journal of Cosmetic Science” Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.
April 2026 in “BMC Biotechnology” Curcumin spanlastics are the most effective for cancer therapy due to their strong antimicrobial, antioxidant, and antitumor effects.
9 citations
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November 2012 in “Biomolecules & therapeutics” A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.