research Targeting IGF1 ‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
Search
for
Sort by
Research
30 / 1000+ results research Targeting
research Cellular Senescence: Ageing and Androgenetic Alopecia
Ageing and increased senescent cells significantly contribute to common hair loss.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research The Dual Nature of Cellular Senescence: From Aging Signature to Regenerative Catalyst
Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
research Investigating the roles of cellular senescence in embryogenesis and aging
Cellular senescence is crucial for normal embryonic development but contributes to aging in adults.
research Nutritional roles of selenium in cellular and mouse aging
Selenium helps protect cells from aging and damage, especially under stress.
research Do Changes in Chromosomes Cause Aging?
Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Targeting cellular senescence may improve skin aging and disorders.
research The Role of PGC-1α in Aging Skin Barrier Function
PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research A Multidimensional Study Integrating Traditional Chinese Medicine and Network Pharmacology: Exploring the Skin Repair and Anti-Aging Effects of a Specific Combination of Five-Colored Plants
The plant combination effectively repairs skin and delays aging.
research 0950 Exploring hair aging through ex vivo induction of DNA damage and senescence
BrdU speeds up hair follicle aging and reduces hair quality.
research Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes
Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.
research De Novo Design of Anti-Aging Peptides
New peptides can delay aging and improve cell function.
research Research progress on mechanisms of skin aging and anti-aging strategies
Personalized anti-aging strategies are important, considering genetics and lifestyle.
research Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging
miR-21 increases skin aging by reducing SATB1, affecting skin cell function.
research TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells
Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
research Montagna Symposium 2014—Skin Aging: Molecular Mechanisms and Tissue Consequences
The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
research The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review.
Topical CoQ10 can reduce wrinkles and signs of aging.
research Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes
Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
research Homeodynamic Rejuvenation: an adaptive framework for resetting skin aging
The article introduces Homeodynamic Rejuvenation as a framework for addressing skin aging by restoring the skin's ability to manage stress and recover efficiently, rather than merely reversing visible signs of aging. This approach emphasizes homeodynamic plasticity, which is the skin's capacity to maintain function under stress. It integrates homeodynamics with exposome biology to reactivate cellular systems responsible for stress sensing, repair, and recovery. Five core processes—intracellular quality control, regenerative competence, metabolic resilience, cellular integrity, and structural integrity—are crucial for maintaining skin function. Disruption of these processes leads to skin aging, with dermatoporosis as a severe outcome. Homeodynamic Rejuvenation is evaluated through dynamic perturbation–recovery kinetics, linking biological processes to functional and clinical outcomes, thus providing a framework for enhancing skin resilience.
research Skin aging: mechanisms, evaluation, and rejuvenation
The document explores the mechanisms of skin aging, emphasizing the roles of cellular senescence, disrupted communication between skin layers, and dysregulation of the microbiome and hormonal signaling in compromising skin structure and function. It discusses advances in evaluating skin aging through molecular and phenotypic indices, which help assess biological age and the effectiveness of interventions. The paper also highlights rejuvenation strategies, including gene expression rewiring, metabolic and microenvironmental modulation, microbiome adjustments, and hormone regulation, providing a framework for precision interventions and regenerative therapies.
research Reconstructing protein conformations to activate follicular enzyme-nutrient reservoirs for reversing follicle aging
The microneedle patch helps regrow hair by restoring enzyme function in hair follicles.
research Skin aging and barrier dysfunction: bridging current therapies with future genetic and nanotechnological interventions
Nanotechnology in skincare can precisely deliver anti-aging genes to improve skin health.
research 520 The protective effects of Apocynin against ultraviolet B-induced cellular senescence in human keratinocytes
Apocynin may protect skin cells from aging and damage caused by UVB light.
research Editorial: Inflammation, stem cells and wound healing in skin aging
Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Regulation of the Wound Healing Response during Aging
Aging slows wound healing due to weaker cells and immune response.
research Comparative biology of tissue repair, regeneration and aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.