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GlossaryCentrifugation

separates mixture components by spinning to sort densities

Centrifugation is a laboratory technique used to separate components of a mixture based on their density by spinning them at high speeds. When a sample is placed in a centrifuge, the centrifugal force pushes denser particles to the bottom of the container, while less dense particles remain closer to the top, allowing for efficient separation and analysis of different substances.

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research The Impact of Centrifugation Devices and Collection Tubes on Fibrin Characteristics and Growth Factor Release Under High- and Low-Speed Protocols

3 citations , October 2025 in “Dentistry Journal”

Low-speed protocols with certified centrifuges and FDA-approved glass tubes are best for effective PRF outcomes.

research Efficacy of Autologous Activated Platelet-Rich Plasma (AA-PRP) in Androgenetic Alopecia: A Systematic Review and Meta-Analysis

January 2025 in “Open Science Framework”

AA-PRP temporarily increases hair density in androgenetic alopecia but loses effectiveness over time.

research Platelet‐rich fibrin: A review of its role as a new treatment in androgenetic alopecia

April 2024 in “Journal of cosmetic dermatology”

Platelet-rich fibrin might be a promising treatment for hair loss, but more research is needed to confirm its effectiveness.

A Cross-Sectional Study Optimizing Platelet-Rich Plasma Preparation Using Various Centrifugation Speeds and Its Effects on the Platelet Yield

research A cross sectional study optimizing platelet rich plasma preparation using various centrifugation speeds and its effects on the platelet yield

September 2024 in “IP Indian Journal of Clinical and Experimental Dermatology”

The best method for high platelet yield is centrifuging at 1300 rpm then 1600 rpm.

Force-Triggered Density Gradient Sedimentation and Cocktail Enzyme Digestion Treatment for Isolation of Single Dermal Papilla Cells from Follicular Unit Extraction Harvesting Human Hair Follicles

research Force-triggered density gradient sedimentation and cocktail enzyme digestion treatment for isolation of single dermal papilla cells from follicular unit extraction harvesting human hair follicles

October 2024

New methods efficiently isolate dermal papilla cells from hair follicles, preserving their characteristics better than traditional methods.

An Optimized Force-Triggered Density Gradient Sedimentation Method for Isolation of Pelage Follicle Dermal Papilla Cells from Neonatal Mouse Skin

research An optimized force-triggered density gradient sedimentation method for isolation of pelage follicle dermal papilla cells from neonatal mouse skin

May 2023 in “Stem cell research & therapy”

New method efficiently isolates hair growth cells from newborn mouse skin.

research Platelet-Therapeutics to Improve Tissue Regeneration and Wound Healing—Physiological Background and Methods of Preparation

14 citations , July 2021 in “Biomedicines”

Platelet-rich treatments can help improve wound healing and tissue repair.

research Technical Procedures for Preparation and Administration of Platelet-Rich Plasma and Related Products: A Scoping Review

12 citations , December 2020 in “Frontiers in Cell and Developmental Biology”

The review found that the way Platelet-Rich Plasma is made varies a lot, which can change the results of medical treatments.

Fat Transfer for the Management of Soft Tissue Trauma: The Do's and Don'ts

research Fat Transfer for the Management of Soft Tissue Trauma: The Do's and the Don'ts

8 citations , November 2010 in “Facial Plastic Surgery”

Fat transfer can be effective for soft tissue trauma if the patient is chosen carefully and the procedure is done correctly.

research Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells

8 citations , January 2017 in “Methods in molecular biology”

Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.

research Platelet-Rich Plasma in Cosmetic Surgery

5 citations , January 2013 in “Otorhinolaryngology clinics : an international journal”

Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.

Anticoagulant-Free Preparation of Autologous Platelet-Rich Plasma (PRP) / Fluid Platelet-Rich Fibrin (f-PRF): A Pre-Clinical Comparative Performance Study

research Anticoagulant-free preparation of autologous platelet-rich plasma (PRP) / fluid platelet-rich fibrin (f-PRF): a pre-clinical comparative performance study

March 2026 in “Frontiers in Pharmacology”

Exprecell™ is as effective as traditional methods but produces more f-PRF and is simpler to use.

Platelet-Rich Plasma And Platelet Fibrin: Standardized Preparation Protocols, Mechanisms Of Activation, Storage Stability, And Regulatory Frameworks

research PLATELET-RICH PLASMA AND PLATELET FIBRIN: STANDARDIZED PREPARATION PROTOCOLS, MECHANISMS OF ACTIVATION, STORAGE STABILITY, AND REGULATORY FRAMEWORKS

December 2025 in “Eastern Ukrainian Medical Journal”

Standardized protocols are crucial for effective use of platelet-rich plasma and fibrin in tissue regeneration.

research Force-triggered density gradient sedimentation and cocktail enzyme digestion treatment for isolation of single dermal papilla cells from follicular unit extraction harvesting human hair follicles

November 2024 in “Stem Cell Research & Therapy”

A new method improves the isolation of hair follicle cells for better hair growth research.

research Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development

January 2023 in “Theranostics”

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

research Impact of the Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells (AD-SVFs) and Human Adipose-Derived Mesenchymal Stem Cells (AD-MSCs): Enzymatic Digestion Versus Mechanical Centrifugation

124 citations , November 2019 in “International Journal of Molecular Sciences”

Standardized kits improve the quality and consistency of isolating stem cells from fat tissue.

Practices of Production, Storage, and Use of Platelet-Rich Plasma and Related Products in Brazil: A Cross-Sectional Study

research Práticas de produção, armazenamento e utilização do plasma rico em plaquetas e produtos relacionados no Brasil: estudo transversal

1 citations , May 2021

Regulatory measures are needed to ensure safe production and use of platelet concentrates in Brazil.

research Mechanical Fractionation of Adipose Tissue—A Scoping Review of Procedures to Obtain Stromal Vascular Fraction

19 citations , October 2023 in “Bioengineering”

tSVF is effective for treating inflammation-related conditions, with centrifugation being the best method for isolation.

research Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance

15 citations , August 2020 in “Analytical chemistry”

Hair lipids do not protect against humidity.

research Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

11 citations , August 2025 in “Journal of Periodontal Research”

Platelet-rich fibrin (PRF) is better for natural healing, especially in dental and medical treatments.

research Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2

22 citations , August 2015 in “PloS one”

Keratin from hair binds well to gold and BMP-2, useful for bone repair.

research Microgel emulsion loaded with recombinant oil body as a new drug delivery carrier to promote wound repair

May 2022 in “Research Square (Research Square)”

OBEME effectively enhances wound healing and could be a promising carrier for skin treatments.

Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis

research Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis

14 citations , May 2013 in “American Journal of Physiology-endocrinology and Metabolism”

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

research Physico-Chemical Properties of Cationic Niosomes Loaded with Fraction of Rice (Oryza sativa) Bran Extract

14 citations , September 2012 in “Journal of nanoscience and nanotechnology”

Niosomes with rice bran extract could be useful for anti-hair loss products.

research Optimisation of Centrifugal Speed for PRPBAG^®: A Novel Multiple Bag System for Preparing Platelet-Rich Plasma

2 citations , June 2021 in “Bezmialem Science”

The best speed for preparing platelet-rich plasma with PRPBAG® is 1800 rpm.

research Methods and Challenges in Purifying Drug‐Loaded Extracellular Vesicles

15 citations , June 2025 in “Journal of Extracellular Vesicles”

Standardized guidelines are needed to improve drug-loaded extracellular vesicle purification.

research Design of Nanocrystalline Suspension of Dutasteride for Intramuscular Prolonged Delivery

November 2024 in “Nanomaterials”

The nanocrystalline suspension effectively delivers dutasteride over time with minimal inflammation.

research State of the Art in Constructing Gas-Propelled Dissolving Microneedles for Significantly Enhanced Drug-Loading and Delivery Efficiency

12 citations , March 2023 in “Pharmaceutics”

Gas-propelled dissolving microneedles improve drug loading and delivery efficiency.

research A Novel Marker of Tissue Junctions, Collagen XXII

226 citations , May 2004 in “Journal of Biological Chemistry”

Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.

Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis

research Stabilization of epithelial β-catenin compromises mammary cell fate acquisition and branching morphogenesis

1 citations , December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Keeping β-catenin levels high in mammary cells disrupts their development and branching.