November 2020 in “Universal Journal of Pharmaceutical Research” Tacrolimus is a better option than cyclosporine due to fewer side effects.
July 2019 in “International journal of dermatology, venereology and leprosy sciences” Oral cyclosporine works better than betamethasone minipulse therapy for treating Alopecia Areata.
February 2018 in “Biophysical Journal” Cyclosporine A slowly changes cell membranes, explaining some of its effects and side effects.
May 2015 in “Journal of The American Academy of Dermatology” Combination therapy with cyclosporine and low-dose corticosteroid shows favorable long-term results for treating alopecia areata.
January 2002 in “대한피부과학회지” Cyclosporine combined with other treatments can help hair regrow in severe alopecia areata, but it may cause side effects.
July 1995 in “Journal of Dermatological Science” Cyclosporine starts hair growth faster, while minoxidil makes it last longer.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
116 citations
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October 1982 in “The Journal of Pathology” Cyclosporin A is highly toxic to rats, causing severe health issues and death.
55 citations
,
June 1987 in “PubMed” Cyclosporin A significantly increases hair growth in certain areas of mice.
54 citations
,
December 2004 in “PubMed” Cyclosporin A vesicles effectively regrow hair and reduce inflammation in alopecia areata.
25 citations
,
December 1991 in “The Journal of Dermatology” Cyclosporin A promotes hair growth in young nude mice.
23 citations
,
December 1988 in “British Journal of Dermatology” Topical cyclosporin may help delay hair loss.
21 citations
,
August 1984 in “BJOG An International Journal of Obstetrics & Gynaecology” Ovarian function was similar in both treatment groups, but both caused excessive hair growth.
6 citations
,
January 1992 in “Journal of Dermatological Treatment” Topical cyclosporin A may help treat psoriasis but has absorption and side effect challenges.
5 citations
,
January 1991 in “Acta Dermato Venereologica” Topical cyclosporin promotes hair growth.
1 citations
,
January 2004 in “Linchuang pifuke zazhi” Topical cyclosporin-A is recommended for severe alopecia areata.
April 2023 in “Journal of Investigative Dermatology” Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.
January 2003 in “Reactions Weekly” Lowering the dose of cyclosporin caused hair loss that didn't improve even when the dose was increased again.
January 2003 in “Journal of Clinical Dermatology” Cyclosporin promotes hair growth by boosting cell growth and reducing cell death.
January 2000 in “Linchuang pifuke zazhi” Cyclosporin A helps hair grow by increasing certain growth factors.
August 1994 in “Journal of dermatological science” Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.
August 1993 in “Journal of Dermatological Science” Cyclosporin and minoxidil promote hair growth.
15 citations
,
February 1987 in “Archives of Dermatology” Topical cyclosporine lotion led to noticeable hair regrowth in alopecia universalis.
8 citations
,
January 2008 in “Annals of Dermatology” Combining Cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata.
7 citations
,
January 2017 in “Annals of Dermatology” Oral cyclosporine combined with Pantogar® effectively treats twenty-nail dystrophy.
May 2024 in “International journal of medicine and psychology.” Age-related immune changes significantly affect disease development in other systems.
August 1993 in “Journal of dermatological science”
60 citations
,
March 2014 in “Veterinary dermatology” Cats with atopic dermatitis often have severe, year-round itching and respond well to certain treatments.
20 citations
,
October 2016 in “Veterinary dermatology” Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
10 citations
,
April 2013 in “Veterinary dermatology” A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.