research Recessive Epidermolysis Bullosa Simplex Phenotype Reproduced in Vitro
Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.
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690-720 / 1000+ resultsresearch First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity
Test thyroid function in all obese patients and prioritize weight loss for hormonal balance.
research Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial
Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.
research Effectiveness of Extracellular Vesicle Application in Skin Aging Treatment and Regeneration: Do We Have Enough Evidence from Clinical Trials?
Extracellular vesicles show promise in skin treatments but need more research and standardization.
research International PCOS guideline clinical research priorities roadmap: a co-designed approach aligned with end-user priorities in a neglected women’s health condition
The roadmap calls for better research and funding to improve PCOS diagnosis, treatment, and health outcomes.
research Characterization of Clinical Features of Hospitalized Patients Due to the SARS-CoV-2 Infection in the Absence of Comorbidities Regarding the Sex: An Epidemiological Study of the First Year of the Pandemic in Brazil
Males had more severe COVID-19 symptoms, but their risk of death was only slightly higher than females.
research Higher prevalence of clinical cardiovascular comorbidities in postmenopausal women with self-reported premenopausal hirsutism and/or oligo-amenorrhea
Postmenopausal women with past hirsutism or irregular periods have more heart and lung diseases.
research Therapeutic and Clinical Potential of Adipose-Derived Stem Cell Secretome for Skin Regeneration
Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
research Randomized Placebo-Controlled Clinical Trial of Dutasteride for Reducing Heavy Drinking in Men
Dutasteride helps reduce heavy drinking, especially for those who drink to cope.
research The Effectiveness of Adipose Tissue-Derived Mesenchymal Stem Cells Mixed with Platelet-Rich Plasma in the Healing of Inflammatory Bowel Anastomoses: A Pre-Clinical Study in Rats
Combining stem cells with platelet-rich plasma improves bowel healing in rats.
research Correlation between biochemical and clinical hyperandrogenism parameter in polycystic ovary syndrome in relation to age
The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
research High migratory activity of dermal sheath cup cells associated with the clinical efficacy of autologous cell-based therapy for pattern hair loss
Cells that move well may improve hair loss treatments by entering hair follicles.
research Peculiarities of long-COVID-19 and treatment strategy: a clinical case
Long-COVID can cause lasting symptoms, but treatment with Erbisol drugs may help.
research Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline
Treat significant hirsutism with medication and hair removal; use birth control pills first, adding antiandrogens if needed.
research Partial biotinidase deficiency: Clinical and biochemical features
Children with partial biotinidase deficiency are healthy at birth but may develop symptoms that improve with biotin therapy.
research Novel Vegan Exosome-like Biomimetic Vesicles for Skin and Hair Follicle Protection and Rejuvenation: Structural and Functional Characterization and Placebo-Controlled Clinical Efficacy Studies
Vegan exosome-like vesicles from microalgae improve skin and hair health, reducing wrinkles and enhancing elasticity.
research Mecanismos e aplicações clínicas das tecnologias de laser e luz na dermatologia moderna
Laser and light technologies are used in dermatology for skin treatments and improving outcomes.
research Comparison of the Effect of Auriculotherapy, a Herbal Compound (Aslagh Capsule), and Metformin on the Clinical Symptoms of Polycystic Ovary Syndrome: Randomized Clinical Trial
Auriculotherapy and Aslagh capsules are as effective as metformin for treating PCOS symptoms, with auriculotherapy slightly better for reducing hair growth.
research Pruritus in Lichen Planopilaris and Frontal Fibrosing Alopecia—Clinical Characteristics and Dermoscopic Correlations
Pruritus is common in LPP and FFA, worsened by heat and stress, and relieved by cold, affecting quality of life.
research A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women
Adult women with acne in Iraq often have more severe symptoms and hormone-related issues than younger girls with acne.
research Epidermal stem cells: skin surveillance and clinical perspective
Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research Novel Mutation in Sjögren-Larsson Syndrome Is Associated With Divergent Neurologic Phenotypes
The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.
research HSP90 Inhibition and Cellular Stress Elicits Phenotypic Plasticity in Hematopoietic Differentiation
Inhibiting HSP90 increases cell adaptability and survival under stress.
research A rare LMNA missense mutation causing a severe phenotype of mandibuloacral dysplasia type A: a case report
A rare genetic mutation caused severe symptoms in a 6-year-old girl with mandibuloacral dysplasia type A.
research A decade of hair-loss clinical trials: a registry-based analysis of studies registered on ClinicalTrials.gov
The analysis of 514 hair-loss clinical trials from 2015 to 2025 shows an increase in trial registrations, particularly after 2020, with a focus on androgenetic alopecia and alopecia areata. Most trials are concentrated in North America and involve pharmacologic therapies. The study highlights the need for standardized outcome measures and broader population representation, as current trials often have fewer than 100 participants and lack diversity, which limits the generalizability of findings. It also notes the importance of aligning research efforts with clinical needs and improving reporting practices to enhance the applicability of results in treating hair-loss disorders.
research Results of Open-Label non-Randomized Comparative Clinical Trial: “BromhexIne and Spironolactone for CoronаvirUs Infection requiring hospiTalization (BISCUIT)
Bromhexine and spironolactone together reduced COVID-19 symptoms and hospitalization time without side effects.
research Cold Plasma An emerging technology for clinical use in wound healing
Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
research RETRACTED: High‐powered 675‐nm laser: Safety and efficacy in clinical evaluation and in vitro evidence for different skin disorders
The study's findings are unreliable due to retraction.