research Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis
Certain gut bacteria may increase or decrease the risk of male pattern baldness.
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research A guide to the use of bioassays in exploration of natural resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function
Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.
research Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using semi-automated processes with custom-coded software
Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
research Author response: Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Hairlessness in mammals is caused by combined changes in genes and regulatory regions.
research Pattern changes of cutaneous dermatoses among Iraqi women preceding and during the COVID-19 pandemic
During the COVID-19 pandemic, Iraqi women experienced more hair loss and certain skin conditions, while contagious skin infections decreased.
research Author response: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is essential for pH balance and normal cell function in plants.
research Decision letter: Plant Trans-Golgi Network/Early Endosome pH regulation requires Cation Chloride Cotransporter (CCC1)
CCC1 is essential for ion balance and proper plant cell function.
research Hair regrowth treatment efficacy and resistance in androgenetic alopecia: A systematic review and continuous Bayesian network meta-analysis
ALRV5XR is the most effective hair regrowth treatment at 24 weeks.
research EGFR marks a subpopulation of dermal mesenchymal cells highly expressing IGF1 which enhances hair follicle regeneration.
A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.
research Developing Patient-Derived 3D-Bioprinting models of pancreatic cancer
3D-bioprinting models of pancreatic cancer could help personalize treatments but need more testing.
research The Application of the Insulin to C-Peptide Molar Ratio (ICPR) in Primary Screening for Insulin Antibodies in Type 2 Diabetes Mellitus Patients: A Further Quantitative Study on the Relationship Between ICPR and Insulin Antibodies
2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.
research Trends in dermatological presentations at the emergency department of a tertiary hospital in Singapore: a 4-year analysis pre- and during COVID-19
More skin issues appeared in the emergency department during COVID-19, highlighting the need for better dermatology training and resources.
research Rapid Screening of Anticoagulation Compounds for Biological Target-Associated Adverse Effects Using a Deep-Learning Framework in the Management of Atrial Fibrillation
The framework helps predict adverse effects of blood thinners, improving drug selection for atrial fibrillation.
research Effects of the α-ketoglutaric acid on the performance, hair follicle development and antioxidant capacity of Rex rabbits
α-Ketoglutaric acid improves hair growth, rabbit performance, and antioxidant levels.
research The Effects of Single Testosterone Administration and Stress Induction on Steroid Hormone Levels in Hair
Testosterone increases hair testosterone levels, stress raises hair cortisol, and relationship status affects hormone levels.
research Unique Circulating MicroRNA Signatures Distinguish Severe Alopecia Areata from Other Inflammatory Skin Diseases
Unique microRNA patterns can help diagnose and treat severe alopecia areata.
research Budesonide for maintenance of remission in Crohn's disease
Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.
research The Transformative Role of Artificial Intelligence in Plastic and Reconstructive Surgery: Challenges and Opportunities
AI can greatly improve plastic surgery, but ethical care and human aspects must remain a priority.
research Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016–2023)
Myhre syndrome symptoms worsen over time, with specific genetic variants affecting severity.
research The need to screen for anemia in exercising women
Exercising women should be screened for anemia due to its prevalence and impact on performance.
research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature
Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
research Cheating on forensic hair testing? Detection of potential biomarkers for cosmetically altered hair samples using untargeted hair metabolomics
Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.
research Evaluation of noninvasive biospecimens for transcriptome studies
Hair follicles and urine cell pellets are promising for transcriptome studies.
research Past, Present and Future Perspectives of Forensic Genetics
Forensic genetics can now predict physical traits and lifestyle habits, with future advancements expected from new technologies.
research Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19
A standardized drug development platform is essential for efficient and effective drug repurposing, especially during pandemics.
research PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands
PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.
research The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy
PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
research Three-dimensional model of normal human dermal tissue using serial tissue sections
A detailed 3D model of human skin was created to help develop artificial skin.
research A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins
The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.