research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
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960-990 / 1000+ results research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model
Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
research Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity
Type VII collagen absence helps skin development by allowing tissue remodeling.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Foxn1 in Skin Development, Homeostasis and Wound Healing
Foxn1 is crucial for skin development and healing, and altering its expression may aid regenerative medicine.
research Burn wound and therapeutic challenge
Stem cell therapy could improve burn healing but has challenges to overcome.
research Optical Behavior of Human Skin Substitutes: Absorbance in the 200–400 nm UV Range
UGRSKIN absorbs UV like native skin after 21-28 days, making it potentially suitable for clinical use.
research Anatomy and Physiology of Hair
Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
research Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
ABCG2 protein marks stem-like skin cells in human epidermis.
research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance
A specific group of skin stem cells was found to help maintain hair follicle cells.
research Imbalanced redox dynamics induce fibroblast senescence leading to impaired stem cell pools and skin aging
Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
research Chikungunya virus infection in the skin: histopathology and cutaneous immunological response
Chikungunya virus often causes skin issues and inflammation.
research Microneedling: A means of collagen induction therapy
Microneedling is a simple, affordable treatment that helps with scars, wrinkles, stretch marks, and hair growth by boosting collagen.
research Hidradenitis Suppurativa Tunnels: Unveiling a Unique Disease Entity
Hidradenitis suppurativa tunnels worsen the disease and often need surgery because current treatments are not very effective.
research Immunohistochemical Pattern of CD34 Distribution in Different Types of Basal Cell Carcinoma and in Peritumoral Skin
CD34 is absent in most basal cell carcinoma cells but present in surrounding skin.
research Enhanced therapeutic effects of all-trans retinoic acid nanostructured lipid carrier composite gel drug delivery system for alopecia areata
The gel improves hair regrowth and reduces irritation in alopecia areata treatment.
research In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research A Novel Technology to Boost Natural Production of Hyaluronic Acid in the Skin Tissue: Human Histology Study
Combining radiofrequency and ultrasound significantly boosts skin's natural hyaluronic acid production.
research Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo
Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.
research Transient agonism of the sonic hedgehog pathway triggers a permanent transition of skin appendage fate in the chicken embryo
Activating the sonic hedgehog pathway in chicken embryos can permanently change scales to feathers.
research Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia
Injecting a peptide-hyaluronic acid mix improved hair growth in men with hair loss and was safe.
research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research TGFβ signaling regulates lipogenesis in human sebaceous glands cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation
TIP39 and PTH2R help control calcium levels and skin cell development.
research Vitamin D and calcium signaling in epidermal stem cells and their regeneration
Vitamin D and calcium are important for skin stem cell function and wound healing.
research Chrysanthemum species used as food and medicine: Understanding quality differences on the global market
Some Chrysanthemum samples from the USA, Europe, and China differ in quality and some contain harmful cadmium.
research Integrated analysis of miRNAs and mRNA profiling reveals the potential roles of miRNAs in sheep hair follicle development
Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Impact of constant light exposure during pregnancy on skin of neonatal New Zealand rabbits: structural and ultrastructural study
Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.