489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
355 citations
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January 2017 in “Journal of the American Academy of Dermatology” JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.
346 citations
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April 2020 in “Frontiers in Oncology” EMT and metabolic pathways help cancer cells resist treatment and spread.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
269 citations
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October 2017 in “International Journal of Molecular Sciences” Improving mesenchymal stromal cell therapies requires overcoming cell death and optimizing delivery methods.
238 citations
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April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
222 citations
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January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems” Ethosomes can safely and effectively deliver various drugs deep into the skin.
218 citations
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September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
200 citations
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March 2023 in “Nature Reviews Molecular Cell Biology” Quiescent adult stem cells are crucial for tissue repair and maintenance.
149 citations
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June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
60 citations
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December 2020 in “Stem Cell Research & Therapy” ASC-CM is more effective than EV for treating osteoarthritis.
55 citations
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April 2022 in “Frontiers in Immunology” Cholesterol affects coronavirus spread and could be a target for treatment.
53 citations
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July 2018 in “Drug design, development and therapy” Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
49 citations
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December 2018 in “Asian Journal of Pharmaceutical and Clinical Research” The herbal shampoo works well but needs more improvement for better quality and safety.
42 citations
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April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
42 citations
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July 2017 in “Molecular therapy” A form of vitamin E promotes hair growth by activating a specific skin pathway.
40 citations
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September 2019 in “World journal of clinical cases” An elderly man's hair grew back after a treatment that transferred healthy gut bacteria.
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January 2020 in “Frontiers in Genetics” PDGFC gene may help select goats with desirable curly wool traits.
37 citations
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December 2022 in “Acta Pharmaceutica Sinica B” Smart delivery methods for CRISPR gene editing are crucial for clinical success.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
36 citations
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August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
34 citations
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July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
32 citations
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April 2020 in “BMC Developmental Biology” Ocu-miR-205 helps control hair growth in Rex rabbits by affecting cell processes and signaling pathways.
30 citations
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February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
29 citations
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October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
28 citations
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September 2020 in “International Journal of Molecular Sciences” Leucocyte-rich platelet-rich plasma boosts cell activity and helps wound healing.
27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
22 citations
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April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
21 citations
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November 2023 in “Heliyon” Tropical herbs are better for hair care than synthetic additives.
21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.