March 2022 in “Scientific Journal of Kurdistan University of Medical Sciences” Oral contraceptives with desogestrel and drospirenone improve PCOS symptoms.
January 2008 in “Journal of Medicinal Chemistry” Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
2 citations
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July 1998 in “Journal of Investigative Dermatology” The authors confirmed that β-estradiol inhibits hair growth in mice when used at the correct concentration.
8 citations
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August 2011 in “Journal of Medicinal Food” D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
13 citations
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August 2016 in “Reproduction” High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
17 citations
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December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
3 citations
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December 2000 in “International Journal of Cosmetic Science” The study created a new method to test drugs that affect hormone processing in skin.
42 citations
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July 1982 in “PubMed” Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.
9 citations
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August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
11 citations
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April 2017 in “The European Journal of Contraception & Reproductive Health Care” Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
July 2024 in “Reactions Weekly”
January 2025 in “Journal of the Korean Society of Food Science and Nutrition” Combining finasteride and black soybean extract better protects hair cells from damage and may treat hair loss effectively with fewer side effects.
1 citations
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January 2010 in “Endocrine abstracts”
January 2024 in “Reproductive toxicology” Hesperidin helps protect against testicular damage caused by finasteride.
9 citations
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February 2022 in “Biomedicines” Testosterone treatment may change estrogen receptor methylation in AFAB individuals.
7 citations
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December 2017 in “Journal of the European Academy of Dermatology and Venereology” Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
4 citations
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July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Certain hormones can reduce skin oil and hair growth, potentially helping treat acne and excessive hair in women.
7 citations
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December 1971 in “European Journal of Endocrinology” Human hair follicles can process steroid hormones like DHEA.
7 citations
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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
1 citations
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March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
A new lipid-based formula using myristyl myristate can improve estradiol treatment for hair loss.
9 citations
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January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
18 citations
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August 2008 in “Journal of Investigative Dermatology” 17-β estradiol and prednisolone may speed up hair regrowth after chemotherapy.
January 2007 in “Inpharma Weekly” Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.
269 citations
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May 2002 in “Hormones and Behavior” Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
Finasteride causes reproductive changes in male rats.
January 2026 in “Journal of Dermatological Treatment” Oral finasteride may cause more sexual side effects than expected, possibly due to negative publicity and reporting bias.
January 2021 in “Research Square (Research Square)” 150 kHz electromagnetic radiation may improve polycystic ovary condition in rats.
53 citations
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November 2014 in “International Journal of Oncology” Wedelolactone may help prevent bone damage in breast cancer by blocking certain cell signals.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.