research Drug reaction with eosinophilia and systemic symptoms and severe involvement of digestive tract: description of two cases
Severe digestive issues in DRESS need early endoscopy for better treatment.
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870-900 / 1000+ results research Extracellular vesicles as human therapeutics: A scoping review of the literature
Extracellular vesicles show promise as treatments but need more research for safety and effectiveness.
research Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems
TheDES improve drug delivery through the skin but need more safety checks.
research Ozenoxacin suppresses sebum production by inhibiting mTORC1 activation in differentiated hamster sebocytes
Ozenoxacin reduces sebum production, helping manage acne.
research Antioxidant potential, anti-inflammatory activity, antidiabetic and cardioprotective effect of Microsechium helleri(Peyr.) Cong.
Microsechium helleri extract has antioxidant, anti-inflammatory, antidiabetic, and heart-protective benefits.
research Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer
Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.
research Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Consequences of Skin Barrier Dysfunction
A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
research Valproate-induced thrombocytopenia
Valproic acid can cause low platelet counts, especially at high doses or in elderly patients.
research Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis
The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
research Adverse Reactions Following Intradermal Injection of Exosome‐Based Formulations: A Case Series
Unregulated exosome-based injections can cause severe skin reactions and scarring.
research Results of stage I in a phase II randomized bilateral comparison of bexarotene 1% topical gel in alopecia areata
Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.
research Maintenance effect of a once-weekly regimen of a Selenium Disulfide-based shampoo in moderate-to-severe scalp seborrheic dermatitis after initial treatment with topical corticosteroid/salicylic acid
Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research 304 Sephardic Ancestry in Recessive Dystrophic Epidermolysis Bullosa Individuals Carrying the Prevalent c.6527insC Mutation
Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.
research Ethinylestradiol/Chlormadinone Acetate
The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.
research Effect of Neurosteroid Withdrawal on Spontaneous Recurrent Seizures in a Rat Model of Catamenial Epilepsy
Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.
research Baricitinib Provides Higher Efficacy in Adolescents Relative to Adults With Alopecia Areata Despite More Severe Disease at Baseline: 36-Week Outcomes From BRAVE-AA Trials
research Investigation of the chemical composition of phenolic compounds in Equisetum arvense (L.) extracts of water and ethanol
Horsetail extracts contain phenolic compounds that may help with hair health.
research Berberine-based strategies: novel delivery systems bring out new potential for wound healing
Berberine delivery systems improve wound healing by enhancing bioavailability, reducing inflammation, and promoting tissue regeneration.
research Study the effect of Finasteride microemulsion gel on the treatment of men with mild to moderate Acne
research 7472 Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients
Estrogen alone can lower testosterone in some transfeminine people.
research Small extracellular vesicles from mesenchymal stem cells: A potential Weapon for chronic non-healing wound treatment
MSC-sEVs may effectively treat chronic non-healing wounds.
research PSS37 CATARACT SURGERY GUIDELINES IN EUROPE: A LITERATURE REVIEW AND DOCUMENT SEARCH IN 15 COUNTRIES
Cataract surgery guidelines vary across Europe, and generic finasteride sales for hair loss have grown due to pill splitting.
research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing
CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
research Tyrosine kinase inhibition and grey hair
Imatinib can repigment grey hair, while SU11428 can cause temporary hair depigmentation.
research Treatment of Polycystic Ovarian Syndrome using Electroacupuncture: A Case Report
Electroacupuncture improved symptoms of PCOS in a 19-year-old woman.
research Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: A possible androgenic bone protective effects induced by exemestane
Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.
research Pharmacological activities of Eclipta alba (L.) Hassk. (Bhringaraja): A Review
Eclipta alba (Bhringaraja) has many medicinal uses, including protecting the liver, promoting hair growth, and reducing inflammation.
research [Visual field defect in a patient given sodium valporate then carbamazepine: possible effect of aminotransferase inhibition].
Anti-epileptic drugs may cause visual and hair side effects due to enzyme inhibition, especially in genetically predisposed individuals.
research Acute Localised Exanthematous Pustulosis
Acute Localised Exanthematous Pustulosis (ALEP) was described as a less recognized variant of Acute Generalised Exanthematous Pustulosis (AGEP), often triggered by drugs like amoxicillin-clavulanic acid. A case study of a 19-year-old boy demonstrated ALEP's presentation as non-follicular pustules on an erythematous base, resolving spontaneously within 7-10 days after discontinuing the drug. The study highlighted dermoscopic features, such as milky-white globules and peripheral dotted vessels, aiding in diagnosis. ALEP was linked to a Type IV hypersensitivity reaction, involving CD8+ T cells and neutrophils, with a potential genetic predisposition shared with pustular psoriasis.