118 citations
,
February 2009 in “Fertility and Sterility” Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.
19 citations
,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
18 citations
,
December 2013 in “Colorectal Disease” Higher prolactin levels in women may be linked to pilonidal sinus disease.
4 citations
,
May 2022 in “BMC Women's Health” High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.
4 citations
,
December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
2 citations
,
February 2014 in “Journal of the European Academy of Dermatology and Venereology” High levels of prolactin in the blood can be linked to widespread hair loss.
September 2022 in “Curēus” The removed ovarian tumor was a rare type of blood vessel tumor that improved the patient's symptoms and hormone levels after surgery.
July 2015 in “Cambridge University Press eBooks” Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
September 2025 in “Reproductive health of woman” Metformin reduces high male hormone levels in women with PCOS.
1 citations
,
May 2021 in “Problemy e̊ndokrinologii” Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
33 citations
,
January 2013 in “Dermatology” Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
16 citations
,
January 2023 in “Cureus” PCOS in teens causes hormonal imbalances, irregular periods, and can lead to infertility and other health issues.
1 citations
,
January 2018 in “Pediatrics in review” A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.
January 2025 in “Pakistan Journal of Health Sciences” The Cyp11a1 gene variation has a weak link to PCOS, but higher di-hydro-testosterone levels are found in PCOS patients.
November 2022 in “Journal of the Endocrine Society” A woman's small ovarian tumor causing high androgen levels was missed by several scans but found during surgery.
May 2021 in “Journal of the Endocrine Society” A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” Androgen levels do not determine the type of PCOS symptoms in young females.
42 citations
,
July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
3 citations
,
July 2019 in “Case Reports in Obstetrics and Gynecology” A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.
February 2021 in “Endocrinology, diabetes & metabolism case reports” A postmenopausal woman's excessive hair growth and hair loss were due to a non-cancerous ovarian condition, treated successfully with surgery.
research ACNE
58 citations
,
January 1997 in “Dermatologic Clinics” Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
40 citations
,
March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
32 citations
,
January 2010 in “Journal of Korean Medical Science” A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.
29 citations
,
November 2011 in “Human Fertility” Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.
17 citations
,
October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
13 citations
,
October 2002 in “Journal of Biochemical and Biophysical Methods” Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.
12 citations
,
August 2011 in “European Journal of Endocrinology” Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.