426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
The new biomimetic skin heals wounds faster and better than traditional treatments, without scarring.
32 citations
,
August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
14 citations
,
December 2018 in “The American journal of pathology” Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.
9 citations
,
January 2023 in “Langmuir” Solubility in skin changes with hydration, affecting chemical absorption.
1 citations
,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
1 citations
,
January 2021 in “Brazilian Journal of Medical and Biological Research” Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.
1 citations
,
April 2025 in “Clinical Cosmetic and Investigational Dermatology” Erlotinib can cause scalp pustules and hair loss, needing early treatment with antibiotics and steroids.
10 citations
,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
1 citations
,
April 2023 in “Scientific Reports” Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
29 citations
,
September 2019 in “Stem Cells International” The PRF/micrograft spray-on skin method effectively healed massive and chronic burns quickly.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
192 citations
,
January 2018 in “Burns & Trauma” Current skin substitutes help heal severe burns but don't fully replicate natural skin features.
15 citations
,
July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
8 citations
,
July 2024 in “Cells” PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
4 citations
,
September 2020 in “Stem Cell Research & Therapy” Xenobiotic-free progenitor cells improve wound healing and blood vessel formation.
4 citations
,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
4 citations
,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
125 citations
,
February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
20 citations
,
September 2004 in “Journal of Anatomy” The inner root sheath evolved to help hair grow safely through the skin in mammals.
8 citations
,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
7 citations
,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
5 citations
,
March 2022 in “Frontiers in Medicine” PRP is effective for treating hair loss, especially with other treatments.
4 citations
,
December 2020 in “Tissue Barriers” Loricrin affects skin immune function and homeostasis.
3 citations
,
July 2023 in “Cells” MG53 helps reduce skin damage caused by nitrogen mustard.
2 citations
,
February 2024 in “International Journal of Molecular Sciences” Negative Pressure Wound Therapy speeds up wound healing by reducing inflammation and promoting skin cell growth.
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
October 2025 in “Animals” miR-200a reduces goose fibroblast growth by targeting PITX2 in the Wnt pathway.
May 2015 in “Hair transplant forum international” Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.
148 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.