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Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.

Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.

Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.

Finasteride treats baldness but may cause lasting sexual side effects.

Leuprolide effectively reduces hair growth in hirsute women at higher doses.

Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.

Blocking testosterone speeds up wound healing in males.

The patient was satisfied with hormone therapy, and her epilepsy remained stable.

Retinoic acid affects male and female muscle energy use and function differently.

Finasteride may cause infertility in rats by affecting epididymis and sperm function.

Reducing 3α,5α-THP in the hippocampus increases seizures in female rats.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Progesterone affects GABA_A receptor function by altering δ subunit levels.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Finasteride impairs sperm quality and fertility in rats, even after stopping treatment.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Finasteride doesn't affect hormone levels in normal men.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Castration significantly reduces prostate size and BPH symptoms.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.