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August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
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June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
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October 2020 in “Pharmaceutics” Polysaccharide-based nanofibers are promising for better wound healing.
163 citations
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October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
96 citations
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September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
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October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
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March 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered scaffolds help heal skin wounds, but perfect treatments are still needed.
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March 2018 in “Biomaterials” Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.
67 citations
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May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
56 citations
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September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
54 citations
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May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
52 citations
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January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
48 citations
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January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
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March 2021 in “Frontiers in Cell and Developmental Biology” Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
45 citations
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January 2021 in “Stem Cell Research & Therapy” The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
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October 2018 in “JCI Insight” Entospletinib effectively prevents eye and skin GVHD in mice.
42 citations
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September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
40 citations
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January 2022 in “Nutrients” Diet can influence inflammatory skin diseases.
40 citations
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August 2021 in “International Journal of Molecular Sciences” The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
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December 2022 in “Acta Pharmaceutica Sinica B” Smart delivery methods for CRISPR gene editing are crucial for clinical success.