January 2021 in “Social Science Research Network” The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.
January 2021 in “Social Science Research Network” The optimized microemulsion with finasteride and cinnamon oil can effectively deliver the drug through the skin without using ethanol.
94 citations
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
Melatonin may protect against cell damage in pancreatitis.
January 2010 in “Research and Practice on Chinese Medicines” Coffee extract and caffeotannic acid can help treat hair loss.
4 citations
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August 2023 in “Journal of Cosmetic Dermatology” Gynostemma pentaphyllum extract may help grow hair and prevent graying.
May 2024 in “Chemical engineering journal” New treatment using Minoxidil and EGCG with ionic liquids improves hair growth and quality for hair loss.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” NOC-4 extract promotes black hair and hair growth effectively.
November 2025 in “Discover Food” Catechins-rich tea extract may help reduce hair loss and promote hair growth.
2 citations
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January 2019 in “Annals of Dermatology” Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
February 2023 in “Reactions Weekly”
July 2023 in “International journal of research publications” Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
32 citations
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September 1966 in “Journal of Investigative Dermatology” 4 citations
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September 1999 in “Journal of Clinical Forensic Medicine” Caffeine in hair might help identify people, but it's not always reliable.
2 citations
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January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
61 citations
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May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
27 citations
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October 1945 in “Endocrinology” Synthetic hormone treatment reduces melanin and hair growth in rats.
January 2019 in “Frontiers in neurology” A nutrition program improved a young woman's concussion symptoms.
35 citations
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June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
50 citations
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January 2018 in “Acta physiologica” Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
5 citations
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October 2020 in “Giornale italiano di dermatologia e venereologia” The phyto-caffeine shampoo reduced hair loss and improved hair strength in women with hair thinning.
42 citations
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July 2014 in “European journal of pharmaceutics and biopharmaceutics” Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
HEM-13HDC, a mix of 8 herbal extracts, helps hair grow and affects hair growth at a molecular level.
January 2022 in “Drugs of Today”
82 citations
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May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
November 2025 in “Journal of Investigative Dermatology” Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
8 citations
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June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
6 citations
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November 2010 in “International Journal of Andrology” New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
July 2022 in “Forte Journal” Higher concentrations of bitter melon extract increase hair growth, with 15% being the most effective.