13 citations
,
August 2016 in “Reproduction” High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
5 citations
,
February 2023 in “Journal of Clinical Medicine” Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.
34 citations
,
April 2023 in “Climacteric” Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.
54 citations
,
November 1995 in “The Journal of Clinical Endocrinology & Metabolism” Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
6 citations
,
January 2017 in “Dermato-endocrinology” ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.
July 2026 in “Frontiers in Endocrinology” A young girl had a hormone-secreting tumor removed, leading to decreased hormone levels, but ongoing monitoring is needed.
4 citations
,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
21 citations
,
December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
6 citations
,
January 2010 in “Case Reports” A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.
10 citations
,
October 2006 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are easier to use and target specific tissues to reduce side effects.
October 2025 in “Journal of the Endocrine Society” A postmenopausal woman had rare symptoms due to a possible ovarian tumor, needing thorough evaluation.
May 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” Ovarian tumors should be considered when postmenopausal women show signs of virilization.
2 citations
,
April 2023 in “BMC endocrine disorders” The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
July 2020 in “Research Square (Research Square)” Higher BMI, IGF-1, and DHEAS levels are linked to advanced bone age in young Chinese girls with early breast development.
September 2024 in “Brazilian Journal of Case Reports” Clomiphene testing can help find ovarian causes of high testosterone in postmenopausal women.
20 citations
,
June 1985 in “Toxicologic Pathology” Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.
169 citations
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November 2009 in “The Journal of Clinical Endocrinology & Metabolism” Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.
3 citations
,
June 2016 in “Gynecological Endocrinology” Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.
1 citations
,
October 2012 in “Gynäkologische Endokrinologie” The document concludes that proper diagnosis and individualized treatment are crucial for managing androgenization in women effectively.
April 2018 in “Gynäkologische Endokrinologie” Testosterone in older women can increase bone density, muscle mass, fat mass, improve memory, and boost libido, but may cause nipple color changes.
4 citations
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March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
75 citations
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June 1999 in “Pediatric Clinics of North America” The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
2 citations
,
January 2014 in “International Journal of Endocrinology” Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.
5 citations
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March 2022 in “Frontiers in Endocrinology” A model using hormone levels, cycle length, and BMI can help identify PCOS in Chinese women but isn't for screening teens.
1 citations
,
August 2015 in “AACE Clinical Case Reports” A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.
October 2016 in “Journal of Case Reports” A rare ovarian tumor can occur without causing male-like symptoms.
Finasteride affects prostate development differently in male and female Mongolian gerbils.
April 2025 in “Middle East Fertility Society Journal” Reference values for nine hormones were established to help diagnose PCOS.
1 citations
,
June 2021 in “Revista de la Facultad de Ciencias Médicas de Córdoba” Postmenopausal virilization can be caused by ovarian hyperthecosis, treatable with surgery.