High concentrations of retinoic acid kill hair follicle stem cells, while low concentrations may help treat skin diseases.
14 citations
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January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
December 2024 in “Stem Cell Research & Therapy” ZO-1 helps hair follicle stem cells renew better by changing their structure.
August 2024 in “Journal of Controlled Release” A new treatment using hybrid vesicles with gold nanoparticles and finasteride significantly improves hair regrowth for androgenetic alopecia.
January 2008 in “Durham e-Theses (Durham University)” Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
170 citations
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November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
18 citations
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November 2016 in “PeerJ” Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
1 citations
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February 2025 in “Cell Cycle” HAP stem cell sheets speed up wound healing and reduce scarring.
17 citations
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December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
1 citations
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May 2025 in “International Immunopharmacology” L-borneol helps skin wound healing by promoting stem cell differentiation.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
September 2023 in “Stem cell reviews and reports” Scientists found a new, less invasive way to get stem cells from horse hair for veterinary medicine.
18 citations
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October 2014 in “In vitro cellular & developmental biology. Animal” Hair follicle stem cells can become neural cells using different methods, with varying efficiency.
12 citations
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January 2018 in “PubMed” Y-27632 helps hair follicle stem cells grow and keep their abilities.
July 2024 in “International Journal of Molecular Sciences” Hemp seed biomaterials may reduce hair loss and improve hair growth.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
44 citations
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March 2012 in “Molecular Carcinogenesis” Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.
36 citations
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February 2017 in “Journal of Cellular and Molecular Medicine” VEGF165 helps hair follicle stem cells become blood vessel cells, aiding new blood vessel growth.
January 2025 in “International Journal of Biological Macromolecules” Decorin helps hair growth by influencing specific cell signals.
June 2026 in “Scientific Reports” Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.
20 citations
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December 2019 in “International Journal of Molecular Sciences” HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.
January 2023 in “Figshare” Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
September 2025 in “Stem Cells Translational Medicine” Lithium chloride-treated stem cell exosomes boost hair growth by activating a specific pathway.
19 citations
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January 2019 in “Animals” PDGFA helps activate hair growth in cashmere goats.
January 2026 in “China National GeneBank DataBase” Human hair follicle stem cells can help heal wounds faster.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
19 citations
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March 2021 in “Applied Materials Today” Silk gel helps skin heal without scars better than other materials.
45 citations
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April 2013 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
October 2025 in “International Journal of Molecular Sciences” Rebamipide may help regrow hair by activating hair follicle stem cells.