724 citations
,
April 2004 in “Lancet Oncology” Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
187 citations
,
April 2019 in “npj Regenerative Medicine” Wharton's jelly secretomes are best for promoting blood vessel growth.
1 citations
,
December 2025 in “Frontiers in Pharmacology” Placental extracts have antioxidant, anti-inflammatory, and immune-boosting effects, but their exact workings are unclear.
63 citations
,
September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
23 citations
,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
3 citations
,
February 2014 in “Advances in Stem Cells” Placenta-derived stem cells can help study and treat spontaneous abortion.
1 citations
,
February 2017 in “International journal of anatomy and research” Understanding fetal skin development helps diagnose congenital skin diseases.
1 citations
,
November 2015 Dental pulp stem cells might not reliably become neurons.
12 citations
,
February 2025 in “Scientific Reports” MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
51 citations
,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
15 citations
,
January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
8 citations
,
February 2020 in “Fertility and Sterility” Operative hysteroscopy is still the main treatment for Asherman syndrome, but more research is needed on post-surgery methods.
February 2026 in “Frontiers in Medical Technology” Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
25 citations
,
July 1991 in “International Journal of Dermatology” Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
9 citations
,
December 2021 in “Journal of Cellular and Molecular Medicine” HAT-MSCs can effectively engulf harmful microbes and particles, aiding infection treatment.
May 2023 in “International journal of molecular sciences” The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
March 2026 in “BMC Veterinary Research” Bovine amniotic membrane with propolis helped a cat's large skin wound heal quickly and fully.
December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
139 citations
,
May 2020 in “Stem Cell Research & Therapy” Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
44 citations
,
January 2015 in “Development” Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
10 citations
,
June 2019 in “Aesthetic Plastic Surgery” Amniotic allograft may be more effective than platelet-rich plasma for midface aging treatment.
9 citations
,
August 2015 in “Tissue Engineering and Regenerative Medicine” Human skin cell byproducts can potentially be used to treat hair loss and promote hair growth.
2 citations
,
November 2023 in “Laboratory Animal Research” Combining stem cell medium and light therapy improves wound healing in diabetic rats.
2 citations
,
April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
24 citations
,
June 2021 in “Annals of Translational Medicine” Human placental extract may help treat osteoarthritis, but more research is needed.
14 citations
,
April 2021 in “International journal of molecular sciences” Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
11 citations
,
January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.