research First‐degree relatives of patients with systemic lupus erythematosus: Autoreactivity but not autoimmunity?
Relatives of lupus patients show signs of immune system activity but not full-blown lupus.
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research Cutaneous manifestations of COVID-19 and vaccines for its prevention: a review of the existing literature
COVID-19 and its vaccines can cause various skin issues due to viral effects, immune responses, and stress.
research Matriptase: Potent Proteolysis on the Cell Surface
Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.
research Alopecia areata
Alopecia areata is a complex condition causing hair loss, linked to genetics and immune system issues, and may be related to other autoimmune diseases; treatments vary in effectiveness.
research The AhR pathway is dysregulated in alopecia areata
Targeting the AhR pathway may help treat alopecia areata.
research Alopecia and autoimmune thyroiditis: the role of selenium and zinc
Correcting selenium and zinc levels may help manage hair loss in autoimmune thyroiditis.
research Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications
Specific miRNA profiles can help diagnose and treat alopecia areata.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Down Syndrome and Autoimmune Disease
People with Down syndrome have a higher risk of autoimmune diseases, so early detection and care are important.
research A Multifunctional MOF Heterojunction for Combating Antibiotic Resistance and Promoting Regenerative Immunity
The microreactor effectively fights antibiotic-resistant infections and promotes tissue healing.
research HIV and alopecia universalis
Azelaic acid's effectiveness in treating certain skin conditions needs more research.
research Nanotechnology-Driven Antioxidants and Immunomodulators for Polycystic Ovary Syndrome (PCOS) Therapy
Nanotechnology offers promising new treatments for PCOS by reducing inflammation and oxidative stress.
research A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health
Sebum is essential for skin health but can cause acne if unbalanced.
research Issue Information
Daily use of emollients from birth may reduce atopic dermatitis in infants, but results are mixed.
research Post-COVID-19 Syndrome Mechanisms, Prevention and Management
Long COVID causes lasting symptoms and needs vaccines for prevention and a team approach for treatment.
research Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs
Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.
research Cyclosporine-Induced Alopecia in Childhood Nephrotic Syndrome – A Case Report
Stopping Cyclosporine A led to hair regrowth in a child with alopecia.
research Elevated serum heat shock protein-70 and interleukin-15: prognostic biomarkers correlating with clinical severity and diagnostic efficacy in active alopecia areata
High levels of HSP70 and IL-15 are linked to more severe alopecia areata.
research Severe Acute SARS-CoV-2 Infection and Long COVID: What Do We Know So Far? New Challenges in Diagnosis and Management
Long COVID causes lasting symptoms in many body systems, needing more research for better treatments.
research Discoid Lupus Erythematosus
Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research 863 Central centrifugal cicatricial alopecia gene expression analysis revealed cholesterol, fatty acid, and mast cell pathways
Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.
research Long non-coding RNA Xist contribution in systemic lupus erythematosus and rheumatoid arthritis
Females are more prone to lupus and arthritis due to X chromosome factors.
research INVESTIGATIONS INTO THE ROLE OF THE X-LINKED EPIGENETIC REGULATOR UTX (KDM6A) IN SELF-RENEWING STRATIFYING EPITHELIA
UTX is important for skin health and its loss can lead to skin issues, especially in females.
research Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata
Epigenetic changes in blood cells may contribute to alopecia areata.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Emotion Dysregulation of Women with Premenstrual Syndrome
Women with PMS tend to use suppression more, leading to higher stress levels.
research Immune signatures of psoriasis: Comparison of genetic expression profiles in psoriasis patients after therapy with biologic agents
Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research Immune modulation of hair follicle regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.