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Standardized methods are needed to understand how process conditions affect extracellular vesicle protein content for skin therapy.

Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

The LMNA mutation affects skin structure even in asymptomatic carriers.

Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.

The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Collagen XVIII is crucial for maintaining tissue structure and function in the brain, kidneys, and hair.

TMPRSS6 is crucial for controlling hepcidin and normal iron absorption.

Targeting METTL1 may help slow papillary thyroid cancer growth and spread.

Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.

NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.

Aging skin cells change their lipid profiles due to stress, affecting skin health.

CMG2 and TEM8 receptors have distinct roles in skin and growth disorders, affecting collagen breakdown and growth.

Acid can block TRPV3 from outside the cell but boost its function from inside.

Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.

BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.

Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Keratin structure changes during keratinization, but the exact model remains uncertain.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.

CCCA involves immune response and metabolism issues, suggesting new treatment options.

A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.

Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.

AGD1's PH domain is essential for its role in root hair growth and polarity.

CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.

The study suggests that a new protease inhibitor can make hair harder to pull out, potentially reducing hair loss.