December 2025 in “International Journal of Innovative Technologies in Social Science” Oral supplements like Vitamin E and Omega-3 can help reduce isotretinoin side effects.
December 2025 in “International Journal of Research in Dermatology” Isotretinoin effectively treats severe acne but has serious side effects and requires careful monitoring.
September 2025 in “Texila international journal of public health” Isotretinoin effectively treats severe acne but can affect blood and inflammation markers, posing risks for some people.
September 2025 in “SKIN The Journal of Cutaneous Medicine” Isotretinoin can cause hair loss, and reducing the dose or using supplements like vitamin D and iron may help.
May 2025 in “Medical Journal of Dr D Y Patil Vidyapeeth” Low-dose isotretinoin and erythromycin effectively treated hair loss in two young sisters.
September 2024 in “Health Problems of Civilization” Isotretinoin effectively treats severe acne but has significant side effects requiring careful monitoring.
July 2024 in “JAAD Case Reports” Isotretinoin may effectively treat hereditary hypotrichosis simplex, a rare hair loss condition.
March 2024 in “Journal of cosmetic dermatology” Isotretinoin can effectively reduce symptoms of frontal fibrosing alopecia.
January 2024 in “Biological trace element research” Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
January 2024 in “International Journal of Trichology” Isotretinoin can cause rare scalp cysts and hair loss, treatable with medication.
Isotretinoin is recommended for acne treatment as it is as effective as cyproterone compound.
August 2023 in “Dermatology Reports” Acne not improved by usual treatments may indicate a genetic disorder.
April 2023 in “Journal of Investigative Dermatology” Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
December 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
September 2022 in “World Family Medicine Journal /Middle East Journal of Family Medicine” Isotretinoin effectively treats acne, with most patients experiencing clear skin.
May 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
Isotretinoin may cause temporary, reversible facial hair growth in some women.
January 2022 in “Surgical & Cosmetic Dermatology” Isotretinoin can rarely cause hair to grow curly.
September 2020 in “Journal of Education, Health and Sport” Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
March 2020 in “European Journal of Pediatric Dermatology” Isotretinoin can cause gynecomastia by lowering testosterone levels.
Isotretinoin delays bone development in young rats.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
January 1999 in “대한피부과학회지” Isotretinoin treatment improved scalp condition and stopped hair loss.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Intermittent isotretinoin can cause various skin, hair, and nail changes.
July 2022 in “Journal of Cosmetic Dermatology” Isotretinoin with tacrolimus may be more effective short-term for treating frontal fibrosing alopecia than finasteride with tacrolimus.
37 citations
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February 2015 in “Journal of the European Academy of Dermatology and Venereology” Oral isotretinoin is the most effective treatment for folliculitis decalvans.
11 citations
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April 2020 in “Journal of Dermatological Treatment” Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.
January 2022 in “Clinical Cases in Dermatology” Some hair loss from medication may reverse after stopping the drug, but treatment options are limited and ongoing research is needed.
September 2017 in “BAUST Journal”
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.