research WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis
WNT5A contributes to keloid scars by promoting cell changes through specific signaling pathways.
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840-870 / 1000+ resultsresearch Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids
miR-26b-5p in macrophage exosomes helps keloids grow.
research Combination cryotherapy and intralesional corticosteroid versus steroid monotherapy in the treatment of keloids
Combining cryotherapy with steroids reduces keloid size more effectively than steroids alone.
research Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment
Proinflammatory fibroblasts and vascular endothelial cells are key in keloid development.
research Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling
Targeting Midkine can help reduce pain and itching in keloids.
research 442 Deciphering the role of keloid fibroblasts in itch
Keloid fibroblasts cause itch and pain by releasing more histamine.
research 0867 The role of schwann cell - macrophage interactions in keloid pathogenesis
Schwann cell and M2 macrophage interactions contribute to keloid growth by increasing matrix deposition.
research Discovery Potential Hub Genes and Pathways in Keloid Fibroblast Development Based on Bioinformatics Analysis
Three genes, BMP4, POSTN, and WNT5A, may help treat keloids.
research Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway
Blocking the HEDGEHOG-GLI1 pathway can reduce keloid growth and may be a potential treatment.
research Three-dimensional analysis of intraepidermal nerve fibres and Langerhans cells in keloids with a focus on pruritus
Itchy keloids on the chest are linked to more nerve fibers and substance P.
research 016 Anesthetics Prior to Keloid Injections: A Painless Approach
Using lidocaine before keloid injections makes the treatment more comfortable for patients.
research 861 Association between keloids and atopic dermatitis: a cross-sectional study at a tertiary care center
Keloids are strongly linked to atopic dermatitis and other health issues.
research An Effective Auricular Keloids Management Method: Excision of the Original Lesion and Postoperative Corticosteroids
research A Prospective Study of Patients Presenting With Pre-sternal Keloids
Pre-sternal keloids are more common in males and can be effectively treated with injections, though recurrences may need more treatment.
research The role of retinoids in the management of cutaneous conditions in blacks
Retinoids help manage skin conditions in black individuals.
research Acne Keloidalis Nuchae
AKN might be a skin marker for metabolic syndrome.
research Laser therapy on darker ethnic skin
Laser therapy on darker skin has higher risks and needs expert handling.
research Pigmentary disorders in black skin
The argon gas-based cryotherapy effectively reduced keloid scars but caused some hypopigmentation and had a recurrence rate, especially in Afro-American patients.
research A clinical study of geriatric dermatoses
Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
research Alopecia in consultations in the dermatology department at Burkina Faso: epidemiologic, clinical, and etiologic aspects
Alopecia in Burkina Faso mostly affects young people, often students, with common causes being tinea and alopecia areata.
research Skin Problems of Blacks
Black patients have unique skin conditions that require specific knowledge for proper treatment.
research Treating Scars of the Chin and Perioral Region
Improve chin and perioral scars with surgery, resurfacing, and other therapies, tailored to each patient.
research Reconstructive Hair Transplantation of the Face and Scalp
Hair transplantation using micrografts and minigrafts is effective and safe for facial and scalp reconstruction with natural-looking results.
research Fibroblast Heterogeneity in Healthy and Wounded Skin
Different types of fibroblasts exist in skin and understanding them can help improve wound healing and treat scars.
research Local Injection of Triamcinolone Acetonide: A Forgotten Aetiology of Cushing’s Syndrome
Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.
research Surgical planing of the skin; dichlorotetrafluoro-ethane as a freezing agent.
Surgical skin planing is safe and effective for treating acne scars using a freezing agent that avoids safety risks.
research Photoepilation: a potential threat to wound healing in a mouse
Photoepilation may disrupt normal wound healing and increase the risk of scars.
research Clinical Snippets
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research A Classic Presentation of Acne Keloidalis Nuchae in a Black Male
Acne keloidalis nuchae causes scarring on the scalp, mainly in African American males, and early treatment is important to prevent lasting damage.
research Support for dermatological research in Sub‐Saharan Africa: insights from African hair and skin research programs
The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.