Search

everythinglearnresearchcommunity

for

Search:↓

Light-emitting diode (LED) photobiomodulation (PBM) is a safe and promising treatment in dermatology, showing moderate efficacy for conditions like inflammatory acne, photoaging, and androgenetic alopecia. Red and near-infrared (NIR) light can improve skin texture and reduce wrinkles, while low-level light therapy (LLLT) significantly increases hair density in androgenetic alopecia. However, consumer devices often have lower irradiance and fluence, leading to limited efficacy. The review highlights the need for standardization of device parameters and high-quality trials, especially for consumer devices, to better establish their clinical benefits. LED therapy is generally supportive rather than primary, with a favorable safety profile and mild, transient adverse effects.

The systematic review and meta-analysis evaluated the effectiveness of ultra-pulse CO2 fractional laser treatment for depressed acne scars, analyzing data from 6 studies with 467 patients. The treatment was found to improve skin smoothness and total skin lesion scores, with a 37.6%±9.6% improvement rate after two courses, and was associated with less trauma, faster healing, and minimal adverse reactions. The combination with autologous platelet-rich plasma (PRP) further enhanced effectiveness by promoting collagen regeneration. Although the treatment showed superior curative effects compared to other methods, the study emphasized the need for larger clinical trials to better assess adverse reactions and long-term effects due to small sample sizes and inconsistent outcome measures in the included studies.