research Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review
Total glucosides of paeony can help treat skin conditions but need more research for clinical use.
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research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research Androgen replacement therapy in women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome
Effective PCOS treatments require targeting specific signaling pathways.
research Optimizing clinical monitoring and management guidelines for capivasertib in HR-positive/HER2-negative advanced breast cancer: expert opinion
Capivasertib improves survival in certain breast cancer cases but requires careful management of side effects.
research Differential plasma proteome analysis reveals key proteins associated with insulin resistance in acne vulgaris patients
C4BPA protein may link acne severity and insulin resistance.
research Androgen excess: a hallmark of polycystic ovary syndrome
Excess androgens may cause PCOS, not just be a symptom.
research The Benefits of Dual Inhibition of 5α Reductase
Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
research Androgen Treatment in Adolescent Males With Hypogonadism
Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: e-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research Androgenetic alopecia – Update 2022
research Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics
Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.
research Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment
Current treatments for androgenetic alopecia are complex and promising, but more research is needed.
research Advances in Laser Therapy for Hidradenitis Suppurativa: A Systematic Assessment of Current Evidence
Laser therapy effectively treats all stages of hidradenitis suppurativa, offering a reliable alternative to medication.
research Ernährungsstörungen des Haares und deren Management
research 3α-androstanediol, but not testosterone, attenuates age-related decrements in cognitive, anxiety, and depressive behavior of male rats
3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Amplicon-based sequencing and co-occurence network analysis reveals notable differences of microbial community structure in healthy and dandruff scalps
Dandruff scalps have unstable microbes, more Malassezia, less Cutibacterium, and targeting Lactobacillus may help.
research Roles of gut microbiota in androgenetic alopecia: insights from Mendelian randomization analysis
Certain gut bacteria may increase or decrease the risk of male pattern baldness.
research Adult female acne: a guide to clinical practice
Adult female acne requires personalized treatment and maintenance to prevent relapse.
research Enhancing Skin Anti-Aging through Healthy Lifestyle Factors
Healthy lifestyle changes can significantly improve skin health as you age.
research Efficacy of metformin therapy in adolescent girls with androgen excess: relation to sex hormone–binding globulin and androgen receptor polymorphisms
Metformin works better for adolescent girls with PCOS who have certain genetic variations.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Hormone replacement therapy in morphine-induced hypogonadic male chronic pain patients
research State of the Science Burn Research: Burns in the Elderly
Burn care for the elderly needs improvement, with more research and specific guidelines required.
research Exploring machine learning strategies for single-cell transcriptomic analysis in wound healing
Machine learning and single-cell analysis improve understanding and treatment of wound healing.
research Dietary Influences on Skin Health in Common Dermatological Disorders
A balanced diet with proteins, vitamins, and minerals is crucial for managing skin disorders.
research Insights into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity
COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
research Research progress in the treatment of non-scarring alopecia: mechanism and treatment
New treatments are needed for non-scarring alopecia due to current limitations.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.