January 2025 in “Dermatology Research and Practice” Higher activity in lichen planopilaris is linked to certain immune and tissue genes.
March 2026 in “Dermatology Reports” FFA has higher long-term remission rates than LPP.
2 citations
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December 2011 in “[Thesis]. Manchester, UK: The University of Manchester; 2011.” Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
April 2019 in “Journal of Investigative Dermatology” Lichen planopilaris involves disrupted fat metabolism, increased scarring, and mast cell activity.
12 citations
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November 2023 in “Skin Appendage Disorders” JAK inhibitors might help treat Lichen Planopilaris, but more research is needed.
June 2023 in “Journal of dermatology for physician assistants” Lichen planopilaris should be considered when diagnosing hair loss in people with darker skin as it may be often missed.
1 citations
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July 2022 in “PLOS ONE” The study concluded that people with Lichen Planopilaris have a more diverse scalp bacteria and different metabolic pathways compared to healthy individuals.
49 citations
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
Poly-L-lactic acid injections can cause hair loss and skin issues.
44 citations
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June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
April 2025 in “Health Science Reports” PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.
June 2025 in “British Journal of Dermatology” Lichen planopilaris may have a genetic link.
2 citations
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June 2016 in “Oral Surgery Oral Medicine Oral Pathology and Oral Radiology” Oral lichen planus can appear before lichen planopilaris.
September 2023 in “Bulletin of the Medical Institute of Continuing Education” Early and accurate treatment of Lichen Planopilaris is crucial to prevent permanent hair loss in men.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Lichen planopilaris in men often affects the scalp, eyebrows, arms, legs, and beard, with many having family members with hair loss.
1 citations
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December 2015 in “TURKDERM” Lichen planopilaris can be accurately diagnosed and effectively treated.
2 citations
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September 2025 in “Future Journal of Pharmaceutical Sciences” Lupeol shows promise for hair growth but needs better absorption and safety testing.
Patients with lichen planopilaris have a higher risk of heart disease.
1 citations
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December 2024 in “Archives of Iranian Medicine” Tofacitinib may help treat Lichen Planopilaris, but more research is needed.
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.
June 2017 in “Journal of The American Academy of Dermatology” Women in Australia report different signs of facial aging compared to women in the US, UK, and Canada; men with Lichen planopilaris often have hormonal abnormalities and thyroid disease.
19 citations
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April 2018 in “International Journal of Dermatology” People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.
May 2025 in “Frontiers in Genetics” A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.
44 citations
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February 2017 in “Journal of the American Academy of Dermatology” Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.
47 citations
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June 2014 in “Journal of Dermatological Treatment” Most treatments for lichen planopilaris were found to be generally unsatisfactory.
76 citations
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June 2008 in “Journal of the American Academy of Dermatology” The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.
14 citations
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May 2018 in “Journal of the American Academy of Dermatology” Platelet-rich plasma might be a new way to treat lichen planopilaris.
1 citations
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May 2022 in “Journal of Drugs in Dermatology” Low-dose naltrexone and platelet-rich plasma can regrow hair in lichen planopilaris.
19 citations
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July 2017 in “Clinical and experimental dermatology” Men with lichen planopilaris had earlier onset than women, and treatment usually improved the condition.
4 citations
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May 2020 in “Journal of The American Academy of Dermatology” Cicatricial pattern hair loss is likely advanced common baldness, not a type of lichen planopilaris.