research Formulation, Evaluation and Stability Studies of Dutasteride Loaded Niosomal Gel
The gel effectively delivers dutasteride for hair loss treatment and remains stable for 90 days.
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510-540 / 1000+ results research The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening
Microspheric skin organoids can be used for drug testing, identifying Minoxidil as a Wnt pathway activator.
research Development of a 3D In Vitro Model of Dupuytren’s Disease as a Platform for Drug Screening
A 3D model of Dupuytren’s disease was developed for better drug testing.
research A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection Studies
A new lab-grown lung model helps study adenoviruses and test antiviral drugs.
research Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis
3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
research Biopharmaceutical characterization of carbopol gel for the dermal application of melatonin
The gel can effectively deliver melatonin through the skin.
research A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin
Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
research The Mediated Body
The article concludes that contemporary visual culture emphasizes body modification, yet it also reveals societal denial of this trend.
research A mechanism-informed deep neural network enables prioritization of regulators that drive cell state transitions
A new neural network helps identify key regulators in cell changes, aiding in understanding diseases and finding new treatments.
research Merkel cell differentiation in trichoblastoma
Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.
research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
research Microneedles: A Promising Therapeutic Strategy for Next-Generation Drug Delivery, Diagnosis and Biosensing
Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
research Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch
The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.
research Self Organized Skin Equivalent by Epithelial and Fibroblast Cells on Polycaprolactone Electrospun Mat with Porous Fibers
Researchers created a potential skin substitute using a biodegradable mat that supports skin cell growth and layer formation.
research Beta Human Papillomavirus and Merkel Cell Polyomavirus in Skin Neoplasms
Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.
research Epithelial cell migration on laminins
Collagen XVII and CD151 affect cell movement, with CD151 inhibiting migration when bound to integrins.
research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Rejuvenation by Design: Building Cosmetic Products with Extracellular Vesicle Technology, the Example of Exo.Reset®
Exo.Reset® uses extracellular vesicle technology for skin rejuvenation.
research 532P Analyses of patient-reported outcomes (PROs) with mirvetuximab soravtansine (MIRV) versus standard chemotherapy in the randomized phase III FORWARD I study in ovarian cancer (GOG 3011)
Mirvetuximab soravtansine improves quality of life and reduces symptoms more than standard chemotherapy in ovarian cancer patients.
research 3D printed microneedles: revamping transdermal drug delivery systems
3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.
research Effect of a portable light emitting diode device on wound healing in a rat model
The portable LED device speeds up wound healing.
research Hydrogel-mediated extracellular vesicles for enhanced wound healing: the latest progress, and their prospects for 3D bioprinting
Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.
research Silicone elastomer gel impregnated with 20(S)-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery
research Adaptive minirhizotron for pepper roots observation and its installation based on root system architecture traits
The new microrhizotron tool effectively observes and measures pepper plant roots non-destructively.
research Nanoemulgel as an innovative platform for phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research Frequent downregulation of DMBT1 and galectin‐3 in epithelial skin cancer
DMBT1 and galectin-3 may help suppress epithelial skin cancer.
research 0843 N6-methyladenosine RNA modification promotes keratinocyte proliferation and cutaneous wound repair through regulation of MTOR stability
Increasing m6A levels can improve skin cell growth and wound healing.
research Human acellular amniotic membrane incorporating exosomes from adipose-derived mesenchymal stem cells promotes diabetic wound healing
A special membrane with cell particles helps heal diabetic wounds faster.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
research Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche
The hydrogel promotes better wound healing by creating a fetal-like environment.