13 citations
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January 2015 in “Molecular Pharmaceutics” Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.
1 citations
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November 2023 in “Cosmetics” Surfactants damage hair, but sealing the cuticle can prevent this.
March 2012 in “Korean Journal of Microscopy” Quantum dot nanoparticles can penetrate skin and reach sebocytes through hair follicles.
January 2005 in “Seibutsu Butsuri/Seibutsu butsuri” Chemical treatments damage hair more than UV exposure, making it thinner and less flexible.
16 citations
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March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
66 citations
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February 1985 in “Archives of dermatological research” Hair dyes penetrate the scalp very minimally, less than 1%.
4 citations
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May 2022 in “Future Journal of Pharmaceutical Sciences” Melatonin-loaded microemulsion could be a promising treatment for hair loss.
24 citations
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February 2007 in “Laser Physics Letters” Caffeine shampoo penetrates hair follicles deeply and stays for up to 48 hours.
56 citations
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January 1996 in “Journal of Forensic Sciences” Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
6 citations
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May 2022 in “Pharmaceutics” Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.
7 citations
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January 2020 in “Skin Pharmacology and Physiology” Standard nail varnish effectively prevents follicular penetration of certain substances.
161 citations
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April 2006 in “Journal of Investigative Dermatology” Liposomes with certain properties can effectively deliver drugs deep into hair follicles.
35 citations
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June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
January 2009 in “The Chinese Journal of Modern Applied Pharmacy” The Potts-Guy model best predicts skin permeability for the tested drugs.
9 citations
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January 2016 in “Journal of Controlled Release” Local hypobaric pressure can significantly improve drug delivery through the skin.
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May 2019 in “Journal of pharmaceutical sciences” Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.
1 citations
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February 2023 in “International journal of research - granthaalayah” Electromagnetic energy from wound dressing paste can disrupt skin lipid droplets, possibly affecting cancer development.
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
52 citations
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August 1978 in “Journal of Applied Polymer Science” Human hair's ability to get wet is complex and can change with treatments, damage, and environment.
The new skin cream with zinc oxide nanoparticles is stable, spreads well, and doesn't deeply penetrate the skin.
May 2024 in “Journal of biomaterials science. Polymer ed.” The three-layer microneedle system effectively delivers minoxidil into the skin, showing potential as a safe and efficient treatment for hair loss.
47 citations
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November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
10 citations
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May 2016 in “Polymer” New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
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December 2024 in “International Journal of Pharmaceutics” Dissolving microneedle patches can effectively deliver drugs over time.
January 2018 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” Nanocarriers can improve skin treatments by effectively delivering drugs and enhancing skin hydration.
January 2017 in “Isan Journal of Pharmaceutical Sciences” A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.
19 citations
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January 2020 in “Journal of Biophotonics” A PEG-400/oleic acid mixture best improves drug delivery monitoring through hair follicles.
43 citations
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November 2012 in “Pharmaceutical research” Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.
5 citations
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January 1994 in “Skin Pharmacology and Physiology” Minoxidil absorption in skin is slowed by cleansing, depends on how long it stays on the skin, and is not much affected by reapplication.
48 citations
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April 2019 in “ACS Applied Materials & Interfaces” A new method for delivering drugs through the skin using biodegradable particles was found to be effective.