research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
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research Modulating the stem cell niche for tissue regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research HAIR MATRIX CELL KINETICS: A SELECTIVE REVIEW
Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
research The cycling hair follicle as an ideal systems biology research model
The hair follicle is a great model for research to improve hair growth treatments.
research Gap junctions in Turing-type periodic feather pattern formation
Gap junctions help control feather pattern formation in chickens.
research Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?
Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.
research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Recent advances in glycopeptide hydrogels: design, biological functions, and biomedical applications
Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
research External light activates hair follicle stem cells through eyes via an ipRGC–SCN–sympathetic neural pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities
Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
research Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles
Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
research In vitro and in vivo investigations of the wound healing effect of crude Spirulina extract and C-phycocyanin
Spirulina extract and C-phycocyanin may help heal wounds.
research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Photobiomodulation in Cells’ Repair
Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Fetal wound healing using a genetically modified murine model: the contribution of P-selectin
P-selectin is not the only factor that prevents scarring in fetal wound healing in mice.
research 1301 STIM1, but not STIM2, is the calcium sensor critical for sweat secretion
STIM1 is essential for sweat secretion.
research PENAPISAN SENYAWA DARI REMPAH-REMPAH KHAS INDONESIA TERHADAP MMP9 DAN TNFα SEBAGAI TARGET PENYEMBUHAN LUKA DIABETES DENGAN METODE PENAMBATAN MOLEKUL
Procyanidin from Indonesian spices may help heal diabetic wounds.
research Hair follicle stem cell cultures reveal self‐organizing plasticity of stem cells and their progeny
The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
research Three-row stereocilia model predicts mammalian hair bundle behavior
The model explains how mammal ear hair cells respond to sound and adapt.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
research Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Sodium alginate cross-linked hydroxypropyl methylcellulose/hydroxyapatite nano biomaterial mediated with zinc to promote bone tissue healing
The zinc-doped nanocomposite helps heal bone tissue effectively.
research Slowly Does It
Special astrocytes improved learning and memory in rats after a stroke.