research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
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450-480 / 1000+ resultsresearch Regulation of stem cell function by protein ubiquitylation
Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
research Down-regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in XenopusMelanophores
Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
research Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration
Biomaterials can help heal wounds without scars and regenerate skin features.
research Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging
Epigenetic and metabolic changes affect stem cell function and aging in skin.
research The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research The Immun System Response İn Covıd-19 Infectıon İn Polycystıc Ovary Syndrome
Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.
research Effects of Biomaterials Derived from Germinated Hemp Seeds on Stressed Hair Stem Cells and Immune Cells
Hemp seed biomaterials may reduce hair loss and improve hair growth.
research Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege
Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans
Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
research Editor's evaluation: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
research T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
research <p>The regenerative potential of skin and the immune system</p>
The skin's immune system helps it regenerate and fight infections.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Immune-Molecular Link between Thyroid and Skin Autoimmune Diseases: A Narrative Review
Thyroid and skin autoimmune diseases share genetic and immune links, affecting both tissues.
research Role of the SOX family in cancer immune evasion: Emerging player and promising therapeutic opportunities
Targeting SOX proteins may improve cancer treatment by restoring immune function.
research Biocompatible exosomes derived from Pinctada martensii mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway
Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
research Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair
NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
research Toll-like receptor 4 (TLR4): new insight immune and aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research Exploring the hair follicle immune privilege state in nonsegmental vitiligo
Hair follicles in nonsegmental vitiligo are better protected from immune attacks than in alopecia areata.
research Hair follicle immune privilege and its collapse in alopecia areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes
Females have stronger immune responses to COVID-19 than males, leading to better outcomes.
research Immune Privilege Collapse and Alopecia Development: Is Stress a Factor
Stress may trigger hair loss by affecting immune protection in hair follicles.
research IL-15 in T-Cell Responses and Immunopathogenesis
IL-15 is key for T cell function and could help improve treatments for immune-related diseases.
research The Role of Nutrition in Immune-Mediated, Inflammatory Skin Disease: A Narrative Review
Diet can influence inflammatory skin diseases.
research The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling
Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
research Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein
Psoriasis patients' immune response to a hair protein depends on their specific gene type.
research The impact of VDR expression and regulation in vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research Identification and characterization of four immune-related signatures in keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Type 2 Cytokine–Dependent Skin Barrier Regulation in Personalized 2-Dimensional and 3-Dimensional Skin Models of Atopic Dermatitis: A Pilot Study
AD-derived keratinocytes effectively mimic inflammation in atopic dermatitis.