research Selection signatures of wool color in Gangba sheep revealed by genome-wide SNP discovery
Wool color in Gangba sheep is influenced by multiple genes and genetic mechanisms.
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540-570 / 1000+ resultsresearch 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway
17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
research Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
research A network pharmacology-based approach to explore mechanism of action of medicinal herbs for alopecia treatment
Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.
research Coffea arabica: An Emerging Active Ingredient in Dermato-Cosmetic Applications
Coffea arabica shows promise for skin care due to its beneficial compounds.
research Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
research Underactive bladder - an underestimated entity
Underactive bladder is hard to diagnose and treat, needing more research.
research Therapeutic use of caffeine in dermatology: A literature review
Caffeine may benefit skin and hair health but more research is needed to confirm its effectiveness in dermatology.
research Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks
Extracellular vesicles could offer precise treatments for psychiatric conditions by targeting brain networks.
research Finasteride, a 5alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat
Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
research The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature
Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.
research Green approach for the recovery of secondary metabolites from the roots of Nardostachys Jatamansi (D. Don) DC using microwave radiations: Process optimization and anti-alzheimer evaluation
Microwave extraction is an effective, eco-friendly way to boost N. jatamansi's anti-Alzheimer's properties.
research Tradescantia-Based Test Systems Can Be Used for the Evaluation of the Toxic Potential of Harmful Algal Blooms
Tradescantia plants can effectively test for the toxicity of harmful algae.
research Does an apple a day keep away diseases? Evidence and mechanism of action
Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.
research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice
A mild botulinum toxin injection improved sperm production and movement in aging mice.
research Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel
Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
research Dysfunction of keratinocyte adhesion
Keratinocyte adhesion problems can cause skin and hair disorders.
research Skinspan: A Holistic Roadmap for Extending Skin Longevity With Evidence‐Based Interventions
The framework suggests sun protection, retinoids, and antioxidants to improve skin longevity.
research Follicular Delivery of Caffeine from a Shampoo for Hair Retention
The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
research Obesity in Adults: Position Statement of Polish Association for the Study on Obesity, Polish Association of Endocrinology, Polish Association of Cardiodiabetology, Polish Psychiatric Association, Section of Metabolic and Bariatric Surgery of the Association of Polish Surgeons, and the College of Family Physicians in Poland
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Double-blind randomized placebo-controlled study of the efficacy and safety of hair loss prevention shampoo containing salicylic acid, panthenol, and niacinamide in alopecia patients
The shampoo with salicylic acid, panthenol, and niacinamide is effective and safe for preventing hair loss in people with alopecia.
research Post-Acute COVID-19 Sequelae – ‘COVID Long Hauler’
Long COVID causes lasting symptoms and needs ongoing care.
research Dietary sodium hyaluronate and eggshell membrane improve skin barrier function and coat health in Ragdoll cats
Sodium hyaluronate and eggshell membrane improve Ragdoll cats' skin and coat health.
research Biochemistry of Vitamin B: Metabolic Regulations, Deficiency Disorders and Emerging Therapeutic Strategies
Vitamin B is essential for metabolism and health, and new therapies are improving its effectiveness.
research Depressive and Anxiety Symptoms in Women with Polycystic Ovary Syndrome: A Meta-Analysis
Women with PCOS are more likely to experience depressive symptoms.
research Drug-associated insomnia: A pharmacovigilance study based on FDA adverse event reporting system
Certain medications, especially nervous system drugs, can cause insomnia, with risks varying by age and gender.
research Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway
Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
research Fenugreek as a Versatile Cosmetic Ingredient: Phytochemical Profile, Skin–Hair Benefits and Formulation Opportunities
Fenugreek is a promising cosmetic ingredient for skin and hair care.