July 2026 in “International Journal of Drug Delivery Technology” This review explores novel drug delivery systems (NDDS) for alopecia treatment, focusing on enhancing drug localization in the pilosebaceous unit to improve follicular retention and reduce systemic exposure and irritation. It discusses various delivery systems, including lipid-based carriers, polymeric nanoparticles, and vesicular systems, which show promise for improved follicular targeting and sustained release. The review emphasizes the potential of combining these systems with biologic therapies like exosomes for enhanced hair regeneration. However, it highlights the need for rigorous safety assessments, manufacturing standardization, and clinical evidence to ensure efficacy and patient compliance, as no single delivery system is universally optimal.
56 citations
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September 2016 in “Pharmaceutical Research” The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.
34 citations
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October 2014 in “European journal of pharmaceutics and biopharmaceutics” The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
11 citations
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October 2017 in “International Journal of Molecular Sciences” A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
September 2025 in “International Journal of Pharmaceutics and Drug Analysis” Ethosomes improve drug delivery through the skin but face stability challenges.
3 citations
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December 2021 Niosomes are a promising method for delivering drugs directly to targeted areas in the body.
December 2025 in “Phytomedicine Plus” Combining herbal medicines with modern delivery systems may improve alopecia treatment.
76 citations
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January 2022 in “Journal of Tissue Engineering” Microneedle patches could replace injections but need more development for better use in medicine.
26 citations
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January 2024 in “Gels” Nanoemulgels could effectively treat skin diseases and may replace or complement current therapies.
25 citations
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June 2024 in “Pharmaceutics” Scaffold-based drug delivery systems improve oral cancer treatment by targeting drugs directly to cancer cells, reducing side effects.
July 2025 in “Future Journal of Pharmaceuticals and Health Sciences” Polyherbal chocolate may help manage PCOS symptoms.
13 citations
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April 2025 in “International Journal of Nanomedicine” The new gallic acid hydrogel speeds up wound healing and reduces scarring.
June 2023 in “International Journal for Research in Applied Science and Engineering Technology” Emulgel improves skin delivery of various drugs better than traditional methods.
21 citations
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March 2021 in “Molecules” The new formulation greatly improved quercetin absorption in rats.
34 citations
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January 2020 in “Expert opinion on drug delivery” New methods like microneedling and nanoparticles can improve hair loss treatments.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” Minoxidil nanoparticles improve hair growth more effectively than regular minoxidil.
5 citations
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March 2016 in “Drug Development and Industrial Pharmacy” New drug delivery systems improve treatment effectiveness and patient experience.
1 citations
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June 2023 in “Chemical engineering journal” A new microneedle patch treats hair loss effectively with fewer side effects and less frequent use.
April 2026 in “Journal of Nanobiotechnology” A new microneedle system effectively treats hair loss by delivering drugs directly to hair follicles.
January 2016 in “Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver” The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
January 2017 in “Elsevier eBooks” Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
April 2026 in “BioNanoScience” A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.
The new microneedle system improves hair growth in alopecia treatment.
July 2025 in “Pharmaceutics” Transdermal delivery systems show promise for treating hair loss by delivering drugs directly through the skin.
January 2026 in “Biomacromolecules” A new topical method using peptides boosts hair growth effectively with less finasteride and fewer side effects.
January 2025 in “The Pharma Innovation” Nanospanlastic vesicles can improve glaucoma treatment by enhancing drug delivery to the eye.
2 citations
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February 2025 in “Journal of Nanobiotechnology” Modified frameworks with stearic acid enhance drug delivery and promote hair growth.
72 citations
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January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
January 2018 in “Clinical dermatology open access journal” Chitosan is useful in skin treatments because it helps with wound healing and cell growth.