research A skin organoid-based infection platform identifies an inhibitor specific for HFMD
NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
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30 / 784 results research 779 Multicellular skin organoids as a unique modeling platform for skin physiology, injury, and disease
The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
research Human relevant platforms for cutaneous wound healing research: current landscape, translational gaps, and emerging frontiers
A combination of advanced human-relevant models and new technologies is needed to improve wound healing research.
research Human hair regeneration using organoids and hair-on-chip technologies
Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
research The microfollicle: a model of the human hair follicle for in vitro studies
Microfollicles can effectively model human hair follicles for research and testing.
research Experimental Models and Molecular Pathogenesis: An Integrated Review of Alopecia
Current models for studying alopecia are inadequate, and more human-like systems are needed.
research Mechano-encoding hydrogel microspheres for extracellular and pericellular matrix remodeling in musculoskeletal organoids
Hydrogel microspheres can improve the development and effectiveness of musculoskeletal organoids.
research Progress and perspectives on hydrogel-assisted skin organoids
Hydrogel-based methods improve skin organoid development for medical and research applications.
research Biomedical applications of organoids in genetic diseases
Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Advancements in hydrogel-based design and applications of hair follicle organoids
Hydrogel-based hair follicle organoids could help treat hair loss and improve drug testing.
research Exploring the efficacy evaluation model for androgenic alopecia using hair organoids: Transcending conventional hair research
Hair organoids are effective for testing hair loss treatments.
research Microtechnology-based methods for organoid models
Microtechnology methods improve organoid production for medical research.
research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
research A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection Studies
A new lab-grown lung model helps study adenoviruses and test antiviral drugs.
research Merkel cell polyomavirus infection and persistence modelled in skin organoids
Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
3D human skin models show promise for dermatology but face challenges in standardization and cost.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
research Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids
A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Construction strategies of skin organoids: A review
A unified framework is needed to improve skin organoid construction for research and clinical use.
research Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Skin organoids: A new human model for developmental and translational research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research 3D bioprinting of hepatocyte-derived exosome-reinforced skin organoid for efficient skin regeneration
3D bioprinted skin using liver cell exosomes helps heal wounds better.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
Skin organoids can model tuberculosis infection and help test treatments.
research Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells
Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
research Small Intestinal Organoid-Derived SP Cells Contribute to Repair of Irradiation-Induced Skin Injury
Intestinal stem cells can help repair skin damage from radiation.