research Using risk analysis to guide changes to compounding formulae
Risk analysis is important for safely adjusting pharmaceutical formulas while maintaining their quality and effectiveness.
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research Profound bradycardia after addition of diltiazem to a beta blocker.
Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
research Melampus and the cure of Proetus’ daughters
Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.
research Chemical Gastroenterocolitis After the Root Canal Therapy - A Case Report
A man had severe stomach issues after a dental treatment with Formacresol, which improved with a different medication.
research 1492 Prostacyclin pathway to enhance wound healing in diabetic foot ulcers
Treprostinil, a drug, can delay wound healing in healthy cells but doesn't affect diabetic foot ulcer cells, suggesting further research could help understand its role in treating these ulcers.
research Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways
Securinine and ajmaline may effectively treat liver cancer, with securinine being less toxic to normal cells.
research In vitro antibacterial evaluation of aqueous and methanol extracts of Tridax procumbens flower on selected pathogenic organisms
Tridax procumbens flower extracts can kill bacteria.
research Knismesis: the aversive facet of tickle
Light tickling can be unpleasant and may feel worse for individuals with autism.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research Phosphodiesterase inhibitors and prostaglandin analogues in dermatology: A comprehensive review
Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research Iron-curcumin-carboxy PTIO coordinated nanoparticles with anti-inflammatory properties for enhanced diabetic wound healing
Iron-curcumin nanoparticles help heal diabetic wounds faster by reducing inflammation and promoting tissue repair.
research Smart Responsive Microneedles for Controlled Drug Delivery
Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
research Final Report on the Safety Assessment of Hypericum Perforatum Extract and Hypericum Perforatum Oil
St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research فعاليه التأهيل البدنى بمصاحبة حقن البلازما الغنيه بالصفائح الدمويه ضمن منظومة الاستشفاء من إلتهاب وتر عضله فوق الشوكه للرياضيين.
Combining physical rehab with PRP injections helps athletes recover from supraspinatus tendonitis.
research Investigation of Follicular and Non-follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles
Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
research Chemical Gastroenterocolitis after Dental Root Canal Therapy with Camphorated and Mentholated Chlorophenol
Using camphorated and mentholated chlorophenol in dental treatments can lead to severe gastrointestinal issues and hair and nail loss.
research The Identification of multi-target Inhibitors of Wolbachia pipientis and Onchocerca volvulus by molecular simulations
Adapalene, Diosmin, and Azelastine could be repurposed to treat onchocerciasis.
research Laser-Assisted Prostaglandin Analogs in the Treatment of Hypopigmented Scars: A Systematic Review.
Laser-assisted prostaglandin analogs improve hypopigmented scars safely, but more research is needed.
research Zizyphus jujubaprotects against ibuprofen-induced nephrotoxicity in rats
Jujube fruit extract may reduce kidney damage from ibuprofen in rats.
research ¿Novedad o prudencia? El delicado equilibrio en la actualización farmacológica
New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.
research Protein-phosphatase inhibitors block root hair growth and alter cortical cell shape of Arabidopsis roots
research Platelet-Rich Plasma for Knee Osteoarthritis: A Comprehensive Narrative Review of the Mechanisms, Preparation Protocols, and Clinical Evidence
PRP is a promising and safe treatment for early to moderate knee osteoarthritis but needs standardized protocols.
research The Pharma Market as Reflected by Patents
The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Medikamentöse Therapie des benignen Prostatasyndroms (BPS)
Combination drug therapies are more effective for high-risk BPS patients but have more side effects and costs.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
These medications for BPH have known risks and may have new side effects.
research Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review
The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.
research The nocebo effect: A clinicians guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.