81 citations
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72 citations
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November 2020 in “Frontiers in Surgery” L-PRF may help bone growth and healing, but more research is needed.
72 citations
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November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
67 citations
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December 2011 in “Stem Cells and Development” NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.
56 citations
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November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
56 citations
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February 2013 in “International Journal of Molecular Medicine” Growth factors help hair follicle stem cells grow and stay versatile.
54 citations
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May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
50 citations
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February 2022 in “Nanomaterials” Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.
45 citations
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44 citations
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April 2023 in “Genes & Diseases” Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.
44 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” MSC-derived exosomes may help in skin repair and regeneration.
43 citations
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January 2016 in “Oxidative medicine and cellular longevity” THSG from a Chinese plant helps with aging and related diseases.
40 citations
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
39 citations
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January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.
39 citations
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June 2019 in “Frontiers in Endocrinology” Lenvatinib and sorafenib are generally safe but need dose adjustments due to side effects.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
36 citations
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January 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
33 citations
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January 2017 in “Journal of Cutaneous and Aesthetic Surgery” Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.
32 citations
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April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
32 citations
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August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
31 citations
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August 2023 in “ACS Applied Bio Materials” The hydrogels are strong, self-healing, and good for 3D printing and delivering treatments.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
30 citations
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September 2024 in “Pharmaceuticals” Silk fibroin nanofibers may help heal diabetic wounds, but more research is needed.
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February 2023 in “Animals” Hair follicle traits at 6 months can help select cashmere goats for breeding.
29 citations
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January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
28 citations
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January 2023 in “Cell Transplantation” Nanofat with stem cells is promising for treating hair loss, scars, and skin rejuvenation.
28 citations
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February 2021 in “Stem Cell Research & Therapy” Placental cell medium boosts blood vessel growth in lab tests.
27 citations
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January 2016 in “Cellular Physiology and Biochemistry” Bidens pilosa L. extract effectively treats androgen deficiency dry eye in rats.
27 citations
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February 2023 in “Oxidative Medicine and Cellular Longevity” Platelets help heal wounds by transferring mitochondria to cells, reducing stress and cell death.